At the end of 2025, the research group led by Lei Xiaoguang held its annual summary and exchange meeting. The event brought together postdoctoral researchers and Ph.D. students to review their research progress over the past year, exchange academic insights, and discuss future directions of the group.
During the meeting, group members delivered presentations summarizing their work in 2025. Through open discussions and peer feedback, participants reflected on technical challenges encountered in their research and shared valuable experiences in methodology, system implementation, and academic collaboration.
Professor Lei Xiaoguang delivered a concluding address, providing a comprehensive overview of the research group’s achievements in 2025. He highlighted the group’s progress in key research directions, including original theoretical contributions, system-level innovations, and steady advancements toward high-impact publications and practical applications. Professor Lei also acknowledged the dedication and collaborative spirit demonstrated by the group members throughout the year.
Looking ahead, Professor Lei outlined the group’s strategic vision for future development. He emphasized the importance of pursuing high-quality, forward-looking research, strengthening interdisciplinary integration, and fostering independent thinking and innovation among young researchers. The group aims to further enhance its academic influence while addressing critical scientific and technological challenges.
The annual summary meeting not only served as a platform for reflection and communication, but also reinforced a shared sense of purpose and momentum. With a clear roadmap and strong team cohesion, the research group looks forward to continued progress and new breakthroughs in the coming year.
Researchers from Dr. Lei Xiaoguang’s group at Peking University participated in the 3rd National Conference on Plant Metabolic Biology, held from December 3–5. The conference focused on “Intelligent Metabolism and Innovative Health,” bringing together leading scientists to discuss advances in plant metabolism, natural products, and innovative applications in ethnic medicine.
During the meeting, members of the Lei Lab—including postdoctoral fellows and doctoral students—actively presented their latest research progress and engaged in in-depth academic exchanges with peers across the country. PhD student Nianxin Guo delivered a well-received poster presentation showcasing recent work from the group.
Guo’s poster stood out among numerous high-quality submissions and was honored with the Best Poster Award, recognizing both the scientific contribution and the clarity of presentation. This achievement highlights the group’s strong research capabilities in plant metabolic biology and their growing influence in the field.
The Lei Xiaoguang group will continue to advance interdisciplinary research at the interface of plant metabolism, chemical biology, and natural product biosynthesis, contributing to innovative developments in life science research.
Dr. Junping Fan from Prof. Xiaoguang Lei’s research group delivered a high-profile plenary lecture at the 2025 Chinese Pharmaceutical Association Medicinal Chemistry Symposium, held from November 28 to 30 in Urumqi, Xinjiang. As a key invited speaker, Dr. Fan presented the group’s latest progress in innovative drug discovery, showcasing new methodologies and research breakthroughs aligned with the conference theme, “Novel Targets and Technologies Driving Original Drug Innovation.” Her insightful talk attracted strong interest from both academia and industry, sparking productive discussions on cutting-edge medicinal chemistry research and future development trends. Dr. Fan’s participation highlighted the group’s leadership in frontier chemical biology and further strengthened its influence within China’s pharmaceutical innovation community.
Hosted by the iHuman Institute with strong support from ShanghaiTech University, the iHuman Forum has become a world-renowned academic platform in GPCR research and drug discovery, bringing together leading experts from the fields of membrane protein biology, chemical biology, and computational biology. Since its inception, the forum has fostered collaboration across academia and industry, and in 2024 it was officially incorporated into the 17th Pujiang Innovation Forum, underscoring its growing influence as one of ShanghaiTech’s flagship annual scientific events.
This year’s forum focused on four major themes—membrane protein structure and function, chemical biology and drug discovery, in situ structural biology, and computational structural biology and pharmacology. Dr. Yang and Dr. Zhu engaged in in-depth discussions with international scholars and industry researchers, sharing insights from the Lei Lab’s ongoing studies in structure-based drug design and GPCR signaling mechanisms. Their participation highlights the group’s continued commitment to advancing interdisciplinary research at the interface of chemistry, biology, and medicine.
The Ray Wu Scholarship, established in 2008 by the Ray Wu Memorial Fund, is widely regarded as the most prestigious scholarship for doctoral students in the life sciences among the Chinese scientific community. It honors the legacy of Professor Ray Wu, a pioneering molecular biologist who made outstanding contributions to the training of a new generation of Chinese scientists.
Each year, around ten exceptional Ph.D. students in life sciences are selected for this award in recognition of their academic excellence, research innovation, and leadership potential. Dr. Yang’s achievement reflects his outstanding contributions to chemical biology and molecular medicine, as well as the Lei Lab’s ongoing commitment to advancing cutting-edge research at the interface of chemistry and biology.
The research group led by Prof. Xiaoguang Lei actively participated in the Annual Retreat of the Center for Life Sciences (CLS), presenting their latest scientific progress and achievements.
At the meeting, Dr. Fusheng Guo was invited to give a flash talk, where he highlighted the group’s cutting-edge research and engaged the audience with thought-provoking insights. Dr. Yingjie Bai’s poster presentation stood out among many excellent contributions and was honored with the Best Popularity Award, reflecting both the high quality of the research and the strong interest it generated from participants.
Meanwhile, graduate students Yihui Gao and Nianxin Guo also presented posters showcasing their ongoing projects. Their active participation further demonstrated the breadth and vitality of the group’s research endeavors.
The retreat provided an excellent platform for academic exchange and collaboration, and the Lei group’s contributions added to the vibrant scientific atmosphere of the event.
Dr. Dongshan Wu and Dr. Xiang Qiu from our research group attended the 17th International Symposium on Biocatalysis and Biotransformations (BIOTRANS 2025), held in Switzerland. The symposium is a leading international platform for scientists working in the field of biocatalysis and biotransformation. Their participation reflects the group’s continued engagement with the global research community and our commitment to staying at the forefront of scientific developments in the field. The event also provided valuable opportunities for academic exchange and potential future collaborations.
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Annual Summary Meeting of Professor Lei Xiaoguang’s Research Group Held Successfully
At the end of 2025, the research group led by Lei Xiaoguang held its annual summary and exchange meeting. The event brought together postdoctoral researchers and Ph.D. students to review their research progress over the past year, exchange academic insights, and discuss future directions of the group.
During the meeting, group members delivered presentations summarizing their work in 2025. Through open discussions and peer feedback, participants reflected on technical challenges encountered in their research and shared valuable experiences in methodology, system implementation, and academic collaboration.
Professor Lei Xiaoguang delivered a concluding address, providing a comprehensive overview of the research group’s achievements in 2025. He highlighted the group’s progress in key research directions, including original theoretical contributions, system-level innovations, and steady advancements toward high-impact publications and practical applications. Professor Lei also acknowledged the dedication and collaborative spirit demonstrated by the group members throughout the year.
Looking ahead, Professor Lei outlined the group’s strategic vision for future development. He emphasized the importance of pursuing high-quality, forward-looking research, strengthening interdisciplinary integration, and fostering independent thinking and innovation among young researchers. The group aims to further enhance its academic influence while addressing critical scientific and technological challenges.
The annual summary meeting not only served as a platform for reflection and communication, but also reinforced a shared sense of purpose and momentum. With a clear roadmap and strong team cohesion, the research group looks forward to continued progress and new breakthroughs in the coming year.
Postdocs and PhD Students from Lei Xiaoguang’s Group Attend the 3rd National Conference on Plant Metabolic Biology PhD Student Nianxin Guo Receives Best Poster Award
Researchers from Dr. Lei Xiaoguang’s group at Peking University participated in the 3rd National Conference on Plant Metabolic Biology, held from December 3–5. The conference focused on “Intelligent Metabolism and Innovative Health,” bringing together leading scientists to discuss advances in plant metabolism, natural products, and innovative applications in ethnic medicine.
During the meeting, members of the Lei Lab—including postdoctoral fellows and doctoral students—actively presented their latest research progress and engaged in in-depth academic exchanges with peers across the country. PhD student Nianxin Guo delivered a well-received poster presentation showcasing recent work from the group.
Guo’s poster stood out among numerous high-quality submissions and was honored with the Best Poster Award, recognizing both the scientific contribution and the clarity of presentation. This achievement highlights the group’s strong research capabilities in plant metabolic biology and their growing influence in the field.
The Lei Xiaoguang group will continue to advance interdisciplinary research at the interface of plant metabolism, chemical biology, and natural product biosynthesis, contributing to innovative developments in life science research.
Dr. Junping Fan Delivers Plenary Lecture at the 2025 CPA Medicinal Chemistry Symposium
Dr. Junping Fan from Prof. Xiaoguang Lei’s research group delivered a high-profile plenary lecture at the 2025 Chinese Pharmaceutical Association Medicinal Chemistry Symposium, held from November 28 to 30 in Urumqi, Xinjiang. As a key invited speaker, Dr. Fan presented the group’s latest progress in innovative drug discovery, showcasing new methodologies and research breakthroughs aligned with the conference theme, “Novel Targets and Technologies Driving Original Drug Innovation.” Her insightful talk attracted strong interest from both academia and industry, sparking productive discussions on cutting-edge medicinal chemistry research and future development trends. Dr. Fan’s participation highlighted the group’s leadership in frontier chemical biology and further strengthened its influence within China’s pharmaceutical innovation community.
Dr. Jun Yang and Weneng Zhu from Prof. Xiaoguang Lei’s group participated in the 10th iHuman Forum, held at ShanghaiTech University from October 31 to November 1, 2025.
Hosted by the iHuman Institute with strong support from ShanghaiTech University, the iHuman Forum has become a world-renowned academic platform in GPCR research and drug discovery, bringing together leading experts from the fields of membrane protein biology, chemical biology, and computational biology. Since its inception, the forum has fostered collaboration across academia and industry, and in 2024 it was officially incorporated into the 17th Pujiang Innovation Forum, underscoring its growing influence as one of ShanghaiTech’s flagship annual scientific events.
This year’s forum focused on four major themes—membrane protein structure and function, chemical biology and drug discovery, in situ structural biology, and computational structural biology and pharmacology. Dr. Yang and Dr. Zhu engaged in in-depth discussions with international scholars and industry researchers, sharing insights from the Lei Lab’s ongoing studies in structure-based drug design and GPCR signaling mechanisms. Their participation highlights the group’s continued commitment to advancing interdisciplinary research at the interface of chemistry, biology, and medicine.
News Release Dr. Jun Yang, from Prof. Xiaoguang Lei’s group at Peking University, has been awarded the 2025 Ray Wu Scholarship.
The Ray Wu Scholarship, established in 2008 by the Ray Wu Memorial Fund, is widely regarded as the most prestigious scholarship for doctoral students in the life sciences among the Chinese scientific community. It honors the legacy of Professor Ray Wu, a pioneering molecular biologist who made outstanding contributions to the training of a new generation of Chinese scientists.
Each year, around ten exceptional Ph.D. students in life sciences are selected for this award in recognition of their academic excellence, research innovation, and leadership potential. Dr. Yang’s achievement reflects his outstanding contributions to chemical biology and molecular medicine, as well as the Lei Lab’s ongoing commitment to advancing cutting-edge research at the interface of chemistry and biology.
Lei Xiaoguang’s Research Group Showcases Achievements at the CLS Annual Retreat
The research group led by Prof. Xiaoguang Lei actively participated in the Annual Retreat of the Center for Life Sciences (CLS), presenting their latest scientific progress and achievements.
At the meeting, Dr. Fusheng Guo was invited to give a flash talk, where he highlighted the group’s cutting-edge research and engaged the audience with thought-provoking insights. Dr. Yingjie Bai’s poster presentation stood out among many excellent contributions and was honored with the Best Popularity Award, reflecting both the high quality of the research and the strong interest it generated from participants.
Meanwhile, graduate students Yihui Gao and Nianxin Guo also presented posters showcasing their ongoing projects. Their active participation further demonstrated the breadth and vitality of the group’s research endeavors.
The retreat provided an excellent platform for academic exchange and collaboration, and the Lei group’s contributions added to the vibrant scientific atmosphere of the event.
Dr. Dongshan Wu and Dr. Xiang Qiu Represent Our Group at BIOTRANS 2025 in Switzerland
Dr. Dongshan Wu and Dr. Xiang Qiu from our research group attended the 17th International Symposium on Biocatalysis and Biotransformations (BIOTRANS 2025), held in Switzerland. The symposium is a leading international platform for scientists working in the field of biocatalysis and biotransformation. Their participation reflects the group’s continued engagement with the global research community and our commitment to staying at the forefront of scientific developments in the field. The event also provided valuable opportunities for academic exchange and potential future collaborations.
Congratulations to Dr. Xinshui Yu and Dr. Jun Yang on successfully defending their Ph.D. dissertations!
The 13th Chinese National Conference on Chemical Biology
Lei group participate the 13th Chinese National Conference on Chemical Biology and Nianxin Guo receives best poster award
2025 Frontiers in Membrane Protein Structural Biology and Drug Discovery Innovation
2025 Frontiers in Membrane Protein Structural Biology and Drug Discovery Innovation