李 娜

学习工作经历

• 1988、 1991 和 1994 年先后获北京大学理学学士、硕士和博士学位
• 1994-1998 年，北京大学化学学院工作
• 1999-2000，美国堪萨斯大学 药化系 CDDR 博士后
• 2000至今 北京大学化学学院工作

教学：

主讲定量化学分析（中文班和英文班）
主讲分析化学系列小班讨论课
获2008年北京市教育教学成果一等奖。
2011年北京市高等教育精品教材
2016年教育部来华留学英语授课品牌课程
2020年北京市优质本科课程（重点课程）

出版教材：

1. 分析化学——定量化学分析简明教程（第4版），北京大学出版社，2020（主编）
2. Quantitative Chemical Analysis(英文). 北京大学出版社，2009 (主编)
   （海外发行World Scientific Publishing Co Pte Ltd, 2013）
3. 分析化学I（电子课件）. 北京大学出版社, 2007(主编)
4. 仪器分析教程(第3版). 北京大学出版社, 2021 (参编)
5. 分析化学教程学习指导. 北京大学出版社, 2006 (参编)
6. 分析化学教程 . 北京大学出版社, 2005 (参编)
7. 超越分子前沿.科学出版社，2004 (参译)

研究领域和兴趣：

光学传感新原理、新方法。主要兴趣为：
基于金属纳米材料光谱（荧光、局域表面等离子体共振吸收/散射）的生物传感。

2012年以来发表的主要学术论文：

1. Rong Sheng Li, Jiahui Liu, Cong Wen, Yaru Shi, Jian Ling, Qiue Cao, Lei Wang, Hu Shi*, Cheng Zhi Huang*, Na Li*
   Transformable Nano-Antibiotics for Mechanotherapy and Immune Activation against Drug-Resistant Gram-Negative Bacteria
   Sci. Adv. 2023, 9 (34), eadg9601.
2. Rongsheng Li, Cong Wen, Chengzhi Huang*, Na Li*
   Functional Molecules and Nano-materials for the Golgi Apparatus-Targeted Imaging and Therapy
   TRAC-Trend. Anal. Chem. 2022, 156(15), 116714.
3. Xi Wu, Rongsheng Li, Tiancheng Lai, Guangyu Tao, Feng Liu, Na Li*
   A Universal Nanoparticle Counting Platform for Tetraplexed Biomarkers by Integrating Immuno-recognition and Nucleic Acid Hybridization in One Assay
   Anal. Chem. 2021, 94, 1687316879.
4. Rong Sheng Li, Jia Hui Liu, Hu Shi*, Ping Ping Hu, Yao Wang, Peng Fei Gao, Jian Wang, Moye Jia, Hongwei Li, Yuan Fang Li, Chengde Mao*, Na Li*, Cheng Zhi Huang*
   Transformable Helical Self-Assembly for Cancerous Golgi Apparatus Disruption.
   Nano Lett. 2021, 21 (19), 8455–8465
5. Rongsheng Li, Jiahui Liu, Yuan Yan, Chuanyang Su, Tiancheng Lai, Yunwen Liao, Yuan Fang Li, Na Li*, Cheng Zhi Huang*
   Aggregation-Enhanced Energy Transfer for Mitochondria-Targeted ATP Ratiometric Imaging in Living Cells.
   Anal. Chem. 2021, 93 (34), 11878–11886
6. Guangyu Tao, Xiao Xu, Rong Sheng Li, Feng Liu, and Na Li*
   Nonamplification Multiplexed Assay of Endonucleases and DNA Methyltransferases by Colocalized Particle Counting
   ACS Sens., 2021, 6, 1321–1329
7. Guangyu Tao, Tiancheng Lai, Xiao Xu, Yurou Ma, Xi Wu, Xiaojing Peo, Feng Liu, Na Li*
   Colocalized Particle Counting Platform for Zeptomole Level Multiplexed Quantification
   Anal. Chem., 2020, 92, 3697–3706
8. Tian Li, Xi Wu, Guangyu Tao, Haoyan Yin, Junlong Zhang, Feng Liu, Na Li*
   A simple and non-amplification platform for femtomolar DNA and microRNA detection by combining automatic gold nanoparticle enumeration with target-induced strand-displacement
   Biosens. Bioelectron. 2018, 105, 137–142.
9. Xiaojing Pei, Tiancheng Lai, Guangyu Tao, Hu Hong, Feng Liu, and Na Li*
   Ultra-specific multiplexed detection of low-abundance single-nucleotide variants by combining masking tactic with fluorescent nanoparticle counting
   Anal. Chem., 2018, 90, 4226–4233
10. Xiaojing Pei, Haoyan Yin, Tiancheng Lai, Junlong Zhang, Feng Liu, Xiao Xu*, Na Li*
    Multiplexed Detection of Attomole Nucleic Acids Using Fluorescent Nanoparticle Counting Platform
    Anal. Chem., 2018, 90, 1376–1383
11. Guangyu Tao, Yang Chen, Ruoyun Lin, Jiang Zhou, Xiaojing Pei, Feng Liu, Na Li
    How G-quadruplex topology and loop sequences affect optical properties of DNA-templated silver nanoclusters
    Nano Res. 2017, 11, 223–2247
12. Ruoyun Lin, Guangyu Tao, Yang Chen, Mingxing Chen, Feng Liu, and Na Li*.
    Constructing a robust fluorescent DNA-stabilized silver nanocluster probe module by attaching a duplex moiety
    Chem. Eur. J., 2017, 23, 10893–10900
13. Runyun Lin, Chenxi Li, Yang Chen,.Feng Liu, and Na Li*
    Metal-enhanced fluorescence in biosensing applications, "Surface Plasmon Enhanced, Coupled and Controlled Fluorescence", 2017, Edited by Geddes, C. D., Wiley, NJ. (Invited chapter)
14. Tian Li, Xiao Xu, Guoqing Zhang, Ruoyun Lin, Yang Chen, Chenxi Li, Feng Liu, and Na Li*
    'Nonamplification Sandwich Assay Platform for Sensitive Nucleic Acid Detection Based on Aunps Enumeration with the Dark-Field Microscope
    Anal. Chem., 2016, 88, 4188–91.
15. Xiao Xu, tian Li, Zhongxing Xu, Hejia Wei, Ruoyun Lin, Bin Xia, Feng Liu, Na Li*
    Automatic enumeration of gold nanomaterials at single particle level.
    Anal. Chem. 2015, 87, 2576–2581
16. Hongduan Huang, Hejia Wei, Mingjian Zou, Xiao Xu,Bin Xia*, Feng Liu, Na Li*
    Modulating fluorescence anisotropy of terminally labeled dsDNA via the interaction between dye and nucleotides for rational design of DNA-recognition based applications.
    Anal. Chem. 2015, 87, 2748–2754
17. Zhenpeng Zhou, Tian Li, Hongduan Huang, Yang Chen, Feng Liu, Chengzhi Huang,* and Na Li*
    A dual amplification strategy for DNA detection combining bio-barcode assay and metal-enhanced fluorescence modality
    Chem. Commun., 2014, 50, 13373–13376
18. Chenxi Li, Yixin Li, Xiao Xu, Xinyi Wang, Yang Chen, Xiaoda Yang, Feng Liu, and Na Li*
    Fast and quantitative differentiation of single-base mismatched DNA by initial reaction rate of catalytic hairpin assembly.
    Biosens. Bioelectron. 2014, 60, 57–63.
19. Zhenpeng Zhou, Hongduan Huang, Yang Chen, Feng Liu, Chengzhi Huang, Na Li*
    A distance-dependent metal-enhanced fluorescence sensing platform based on molecular beacon design
    Biosens. Bioelectron. 2014, 52, 367–373
20. Xinyi Wang, Mingjian Zou, Hongduan Huang, Yuqian Ren, Limei Li, Xiaoda Yang, Na Li*
    Gold nanoparticle enhanced fluorescence anisotropy for the assay of single nucleotide polymorphisms (SNPs) based on toehold-mediated strand-displacement reaction
    Biosens. Bioelectron. 2013, 41, 569–575
21. Xiao Xu, Yang Chen, Hejia Wei, Bin Xia, Feng Liu and Na Li*
    Counting Bacteria Using Functionalized Gold Nanoparticles as the Light-Scattering Reporter
    Anal. Chem. 2012, 84, 9721–9728.
22. Mingjian Zou, Yang Chen, Xiao Xu, Hongduan Huang, Feng Liu, Na Li*
    The homogeneous Fluorescence Anisotropic Sensing of Salivary Lysozyme Using the 6-carboxyfluorescein-labeled DNA Aptamer
    Biosens. Bioelectron. 2012, 32, 148–154