黄永棋

北京大学 化学学院
2007级研究生 2012年7月毕业
去向：St. Jude Children's Research Hospital博士后，后任山东大学助理教授，再后任湖北工业大学副教授
研究方向：天然无序蛋白质在分子结合过程中的特性
Email:yqhuang_at_pku.edu.cn
English Version

 

简历:

2003年9月-2007年7月，山东大学化学与化工学院，理学学士

2007年9月-2012年7月，北京大学化学与分子工程学院，理学博士

2012年9月-2015年9月，美国St. Jude Children's Research Hospital，博士后

2016年1月-2016年9月，山东大学化学与化工学院，助理研究员

2016年9月-？？？，湖北工业大学，生物工程与食品学院，副教授

 

发表论文:

1. Huaiqing Cao, Yongqi Huang*, and Zhirong Liu*. Interplay between binding affinity and kinetics in protein-protein interactions. Proteins: Struct. Funct. Bioinform. 84 (7), 920-933 (2016).

2. Zhirong Liu and Yongqi Huang. Advantages of proteins being disordered. Protein. Sci. 23 (5), 539-550 (2014). (invited review)

3. Yongqi Huang and Zhirong Liu. Do intrinsically disordered proteins possess high specificity in protein–protein interactions? Chem. Eur. J. 19 (14), 4462-4467 (2013).

4. Zhirong Liu and Yongqi Huang. Evidences for the unfolding mechanism of three-dimensional domain swapping. Protein Sci. 22 (3), 280-286 (2013).

5. Yongqi Huang, Xue Kang, Bing Xia, and Zhirong Liu. Mechanism of 3D domain swapping for Mpro-C: clues from molecular simulations. Acta Phys. -Chim. Sin. 28 (10), 2411-2417 (2012).

6. Iskra Staneva, Yongqi Huang, Zhirong Liu, and Stefan Wallin. Binding of two intrinsically disordered peptides to a multi-specific protein: a combined Monte Carlo and molecular dynamics study. PLoS Comput. Biol. 8 (9), e1002682/1-9 (2012).

7. Yongqi Huang, Huaiqing Cao, and Zhirong Liu. Three-dimensional domain swapping in the protein structure space. Proteins: Struct. Funct. Bioinform. 80 (6), 1610-1619 (2012).

8. Yongqi Huang and Zhirong Liu. Anchoring intrinsically disordered proteins to multiple targets: lessons from N-terminus of the p53 protein. Int. J. Mol. Sci. 12 (2), 1410-1430 (2011).

9. Yongqi Huang and Zhirong Liu. Nonnative interactions in coupled folding and binding processes of intrinsically disordered proteins. PLoS ONE 5 (11), e15375/1-10 (2010).

10. Yongqi Huang and Zhirong Liu. Smoothing molecular interactions: the "kinetic buffer" effect of intrinsically disordered proteins. Proteins: Struct. Funct. Bioinform. 78 (16), 3251-3259 (2010).

11. 黄永棋、刘志荣。天然无序蛋白质: 序列-结构-功能的新关系。 物理化学学报 26 (8), 2061-2072 (2010).
Yongqi Huang and Zhirong Liu. Intrinsically disordered proteins: the new sequence-structure-function relations. Acta Phys. -Chim. Sin.26 (8), 2061-2072 (2010).

12. Yifei Qi*, Yongqi Huang*, Huanhuan Liang, Zhirong Liu, and Luhua Lai. Folding simulations of a de novo designed protein with a βαβ fold. Biophys. J. 98 (2), 321-329 (2010).

13. Yongqi Huang and Zhirong Liu. Kinetic advantage of intrinsically disordered proteins in coupled folding-binding process: a critical assessment of the "fly-casting" mechanism. J. Mol. Biol. 393 (5), 1143-1159 (2009). [422 (1), 156 (2012).]

14. Yongqi Huang, Huifang Li, and Yuxiang Bu. Molecular dynamics simulation exploration of cooperative migration mechanism of calcium ions in sarcoplasmic reticulum Ca2+-ATPase. J. Comput. Chem. 30 (13), 2136-2145 (2009).

 

参加会议：

1. Yongqi Huang, Nonnative Interactions in Coupled Folding and Binding Processes of Intrinsically Disordered Proteins. Poster. Barcelona BioMed Conference on "Intrinsically disordered proteins in biomedicine", Barcelona, Spain. October 4-6, 2010.

2. Yongqi Huang and Zhirong Liu, Nonnative Interactions in the Binding Process of Intrinsically Disordered Proteins: Implication for Interaction Promiscuity and Aggregation. Poster + short talk. The 3rd Asia Pacific Protein Association (APPA) Conference（第三届亚太地区蛋白质科学大会）, Shanghai University, Shanghai, China. May 6-9, 2011.

3. Yongqi Huang, Xue Kang, Bin Xia, and Zhirong Liu, Unfolding simulation of C-terminal domain of SARS-CoV main protease: the swapping core helix. Poster. The 25th Anniversary Symposium of the Protein Society, Boston, Massachusetts, U.S.A., July 23-27, 2011.

 

获奖情况:

1. 2009、2010、2011年，定量生物学中心奖学金二等奖

2. 2009年，北京大学苏州工业园区奖学金

3. 2010年，北京大学东港奖学金

4. 2011年，北京大学钟陈玉蘭奖三等奖学金

5. 2011年，Finn Wold Travel Award, The Protein Society, 美国

6. 2012年，北京大学化学学院2012年优秀博士学位论文