Wgroup member: Guisheng Deng Graduate student ()

Wgroup member: Guisheng Deng Postdoctoral fellow (2000.10 ~ 2002.9) Email: gsdeng@pku.edu.cn Dr. Deng came to join Wgroup in October 2000 as a postdoctoral fellow. His main project is the development of new synthetic methodologies based on a-diazo carbonyl compounds. He discovered Lewis acid controlled regioselective addition reaction of Ti(IV)-enolate to a,b-unsaturated carbonyl compounds. This work has been accepted for publication in Angew. Chem. He also developed a new approach to pyrrole derivatives based on the Rh(II)-mediated diazo decomposition. Dr. Deng obtained his Ph.D. degree from Zhejiang University under the direction of Professor Xian Huang. Guisheng is now an associate professor in the Department of Chemistry, Hunan Normal University, China. Current position: Hunan Normal University; Email: gsdeng@hunnu.edu.cn

Final report for postdoctoral study: Lewis Acid Activated and Controlled Nucleophilic Addition: Investigation on Application and Synthesis of alpha-Diazo Carbonyl Compounds

Publications

(1) Lewis Acids Controlled Regioselective 1,2 and 1,4 Reaction of a, b-Unsaturated Carbonyl Compounds with Ti(IV) Enolates Derived from a-Diazo-b-ketocarbonyl Compounds
Guisheng Deng, Xue Tian, Zhaohui Qu and Jianbo Wang, Angew. Chem. Int. Ed. Engl. 2002, 41, 2773-2776. Click Here

(2) Rh2(OAc)4-Mediated Diazo Decomposition of d-(N-Tosyl)amino-b-keto-a-diazo Carbonyl Compounds: An Novel Approach to Pyrrole Derivatives
Guisheng Deng, Nan Jiang, Zhihua Ma, Jianbo Wang, Synlett, 2002, 1913-1915. Click Here

(3) A Novel Approach to Two-ring Fused Cyclopentenone Derivatives
Guisheng Deng, Xue Tian and Jianbo Wang, Tetrahedron Lett. 2003, 44(3), 587-589.Click Here

(4) Study on the Mass Spectrometry of Diazo Compounds
Zhenpei Yu, Xiaoranhe, Guisheng Deng and Jianbo Wang, J. Inst. Anal. 2003, 22, Suppl. 125.

(5) Regioselective 1, 2-Addition of Ti(IV)-Enolate to alpha, beta–Unsaturated Compounds
Guisheng Deng, Mingyi Liao, Xue Tian, Jianbo Wang
Chin. Chem. Lett. 2005, 16, 589-592.Click here.

(6) New Approaches to Polysubstituted Pyrroles and g-Lactams based on Nucleophilic Addition of Ti(IV) Enolates Derived from a-Diazo-b-keto Carbonyl Compounds to N-Tosylimines
Changqing Dong, Guisheng Deng and Jianbo Wang
J. Org. Chem. 2006, 71, 5560-5564.

(7) Synthesis of Oxygen-containing Heterocyclic Compounds Based on the Intramolecular O-H Insertion and Wolff Rearrangement of a–Diazocarbonyl Compounds
Mingyi Liao, Suwei Dong, Guisheng Deng, Jianbo Wang
Tetrahedron Lett. 2006, 47, 3927-3929.

(8) Cu(I)-Catalyzed Coupling of Diaryldiazomethanes with Terminal Alkynes: An Efficient Synthesis of Tri-Aryl-Substituted Allenes
Chenggui Wu, Fangdong Hu, Zhenxing Liu, Guisheng Deng, Fei Ye, Yan Zhang, Jianbo Wang
Tetrahedron 2015, 71, accepted.