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Contact

Email: conglei@pku.edu.cn
Tel: +86-10-62767947
Office: C601 Chemistry Building
Research Group: Xing Chen Group (https://www.chem.pku.edu.cn/xchengrp/index.htm)

Cong Lei
Associate Research Fellow

Biography

  • 2024-present: Associate Research Fellow, College of Chemistry and Molecular Engineering, Peking University

  • 2019-2024: Postdoctoral Scholar, College of Chemistry and Molecular Engineering, Peking University

  • 2012-2019: Ph.D., Peking-Tsinghua Center for Life Sciences, Peking University

  • 2008-2012: B.S., Lanzhou University


Research Interests

My research focuses on the identification and functional study of plant glycosylated proteins, utilizing chemical biology strategies for high-throughput, tissue-specific, and quantitative analysis of glycosylation in plants. We focus on three major areas:        

1) Development of methods for identifying plant glycosylated proteins.        

2) Large-scale identification of plant glycosylated proteins.        

3) The biological functions of plant glycosylated proteins in growth, development, and stress resistance processes.


Awards

Beijing National Laboratory for Molecular Sciences Junior Fellow


Selected Publications

  1. Lei, C.#, Li, X.#,* Li, W.#, Chen, Z., Liu, S., Cheng, B., Hu, Y., Song, Q., Qiu, Y., Zhou, Y., Meng, X., Yu, H., Zhou, W., Chen, X.*, & Li, J.* “Chemical glycoproteomic profiling in rice seedlings reveals N-glycosylation in the ERAD-L machinery” Mol. Cell. Proteomics, 2024, 24, 100883.

  2. Li, X.#, Lei, C.#, Song, Q., Bai, L., Cheng, B., Qin, K., Li, X., Ma, B., Wang, B., Zhou, W., Chen, X.*, & Li, J.* “Chemoproteomic profiling of O-GlcNAcylated proteins and identification of O-GlcNAc transferases in rice” Plant Biotechnol. J. 2023, 21, 742–753.

  3. Wu, J.#, Lei, C.#, Li, X., Dong, X., Qin, K., Hong, W., Li, J., Zhu, Y.*, & Chen, X.* “Chemoproteomic profiling of O-GlcNAcylation in Arabidopsis thaliana by using metabolic glycan labeling” Israel Journal of Chemistry, 2023, 63, 1-2: e202200065.

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