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Contact

​Email: wen.zhou@pku.edu.cn
Tel: +86-10-62757536
Office: A111 Chemistry Building

Wen Zhou
​Senior Engineer

Biography

  • Senior Engineer, Analytical Instrumentation Centre, (2015-now)

  • Research Scientist, Baxter Healthcare International, US (2012-2015)

  • Postdoctoral Scientist, Wolfe Laboratories, US (2011-2012)

  • Ph.D., University of Michigan (2011)

  • B.S., Peking University (2006)


Research Interests

Structural characterization and quantitation of protein post-translational modifications, e.g. glycosylation, phosphorylation, acetylation and etc..


Facilities (Instrumentation)

  • Fourier Transform Ion Cyclotron Resonance Mass Spectrometer (equipped with ESI/MALDI/DART sources), Bruker

  • Orbitrap Fusion Lumos Tribrid Mass Spectrometer, Thermo Scientific

  • LTQ Orbitrap Elite Mass Spectrometer, Thermo Scientific

  • LTQ Orbitrap XL Mass Spectrometer, Thermo Scientific

  • 5800 MALDI-TOF/TOF Mass Spectrometer, Ab Sciex


Awards

  • Thermo Fisher Scientific Analytical Testing Outstanding Young Talents Award in Universities (2021)

  • Peking University Luye Eminent Young Scholar Fellowship (2019)


Selected Publications

  1. Li, J.; § Zhou, W.; § Zhang, J.; Ma, L.; Lv, Z.; Geng, Y.;* Chen, X.;* Li, J.* O-GlcNAcylation of YTHDF2 antagonizes ERK-dependent phosphorylation and inhibits lung carcinoma. Fundam. Res., 2024, accepted.

  2. Liu, J.; Cheng, B.; Fan, X.; Zhou, X.; Wang, J.; Zhou, W.; Li, H.; Zeng, W.; Yang, P.; Chen, X.* Click-iG: Simultaneous Enrichment and Profiling of Intact N-linked, O-GalNAc, and O-GlcNAcylated Glycopeptides. Angew. Chem. Int. Ed., 2023, e202303410.

  3. Mao, L.; Xiao, H.; Zhao, J-Q.; Diao, Z.; Zhou, W.; Li, H.; Tung, C.; Wu, L.; Cong, H.* Synthesis of Finite Molecular Nanotubes by Connecting Axially Functionalized Macrocycles. CCS Chem. 2022, 4, 3772-3780.

  4. Liang, L.; Wang, Q.; Song, Z.; Wu, Y.; Liang, Q.; Wang, Q.; Yang, J.; Bi, Y.; Zhou, W.*; Fan, L.* O-Fucosylation of CPN20 by SPINDLY Derepresses Abscisic Acid Signaling during Seed Germination and Seedling Development. Front. Plant Sci., 2021, 12, 724144.

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