Biography
Engineer and Senior engineer, College of Chemistry and Molecular Engineering, Beijing NMR Center, Peking University (2011-now)
Research Assistant, Florida State University, National High Magnetic Field Laboratory (2008-2011)
Ph.D., School of Life Science, University of Science and Technology of China (2007)
B.S., Shandong Normal University (2002)
Research Interests
Biomolecular, using solution NMR technology to study structure and dynamics of protein and other biomolecules
NMR technology
Facilities
950 MHz Avance III equipped with a 5 mm 1H-13C / 15N / 2H CPTCI Cryoprobe
800 MHz Avance III equipped with a 5 mm 1H(F)-13C / 15N / 2H CPTCI Cryoprobe
800 MHz Avance III equipped with a 3 mm 1H-13C / 15N / 2H Bruker CPTCI Cryoprobe
Selected Publications
Niu, etc. al, Biomolecular dynamic properties probed by solution NMR, Scientia Sinica Chimica 2020, 50(10):1375-1383.
Niu, etc.al., Residue selective (15)N CEST and CPMG experiments for studies of millisecond timescale protein dynamics., J. Magn. Reson., 2018, 293: 47-55.
Wang, etc.al, Conformation switching of AIM2 PYD domain revealed by NMR relaxation and MD simulation., Biochem. Biophys. Res. Commun., 2016, 473(2): 636-641.
Hou, etc. al., The NMR solution structure of AIM2 PYD domain from Mus musculus reveals a distinct alpha2-alpha3 helix conformation from its human homologues., Biochem. Biophys. Res. Commun., 2015, 461: 396-400.
Niu, et.al., Bruschweiler, Rafael; Chapman, Michael S ; Arginine kinase: joint crystallographic and NMR RDC analyses link substrate-associated motions to intrinsic flexibility., J. Mol. Biol., 2011, 405(2): 479-496.