Biography

• Associate Professor, College of Chemistry and Molecular Engineering, Peking University (2006-now)

• Lecturer, College of Chemistry and Molecular Engineering, Peking University (2001-2006)

• Research Assistant, China Institute of Radiation Protection (1997-1998)

• Ph.D. in Inorganic Chemistry, Peking University (2001)

• M.S. in Radiochemistry, Lanzhou University (1997)

• B.S. in Radiochemistry, Lanzhou University (1994)

Research Interests

• Development of new tumor or hypoxia-targeting molecular probes and new radiolabeling techniques is an important part of our research. It involves organic synthesis, radiolabeling, and in vitro and in vivo evaluation.

• Our current research also involves separation of medical radionuclides, fissionable elements or hazardous radionuclides using ionic liquids as solvents or new materials as adsorbents.

Teaching

• Applied Chemistry Fundamentals

• Coordination Chemistry

Selected Publications

1. Shuo Li, Taiwei Chu* (2024). Preparation and bioevaluation of a novel 99mTc-labelled propylene amine oxime (PnAO) containing two 4-methyl-2-nitroimidazole groups as a promising tumor hypoxia imaging agent. Bioorganic & Medicinal Chemistry Letters, 106: 129773.

2. Zong Guo, Taiwei Chu* (2023). Efficient sorption of Mo(VI) from a synthetic solution of uranium and several fission elements on 8-quinolinol grafted silica. Separation and Purification Technology, 308: 122967.

3. Shuo Li, Taiwei Chu* (2023). Improving tumor/muscle and tumor/blood ratios of 99mTc-labeled nitroimidazole propylene amine oxime (PnAO) complexes with ethylene glycol linkers. Bioorganic & Medicinal Chemistry Letters, 82: 129154.

4. Zong Guo, Taiwei Chu* (2023). Separation of Mo(VI) from U(VI) and other fission elements in synthetic solutions by di-quinolinol chelating ligand in [C4mim][NTf2] ionic liquid. Hydrometallurgy, 215: 105968.

5. Hang Su, Taiwei Chu* (2022). Synthesis and Bioevaluation of the Cyclopentadienyl Tricarbonyl Technetium-99m 2-Nitroimidazole Derivatives for Tumor Hypoxia Imaging. Bioorganic & Medicinal Chemistry Letters, 60: 128583.

6. Renyu Yang#, Damin Wang#, Taiwei Chu* (2020). Synthesis and Bioevaluation of Radioiodinated Nitroimidazole Hypoxia-Imaging Agents by One-Pot Click Reaction, Bioorganic & Medicinal Chemistry Letters, 30: 127386.

7. Zong Guo, Taiwei Chu* (2020). Extraction of tetravalent uranium by N,N,N',N'-tetramethylmalonamide in ionic liquid and spectral investigation of extraction complex. Separation and Purification Technology, 240: 116629.

8. Aining Yao, Feng Qu, Yu Liu，Guangyin Qu，Hao Lin，Shaowen Hu，Xiangyun Wang，Taiwei Chu* (2019). Ionic liquids with polychloride anions as effective oxidants for the dissolution of UO2. Dalton Transactions, 48: 16249-16257.

9. Jin Ding, Hang Su, Fan Wang, Taiwei Chu* (2019). A pre-targeting strategy for imaging glucose metabolism using technetium-99m labelled dibenzocyclooctyne derivative. Bioorganic & Medicinal Chemistry Letters, 29: 1791-1798.

10. Xianteng Yang#, Fan Wang#, Hua Zhu, Zhi Yang*, Taiwei Chu* (2019). Synthesis and bioevaluation of novel 18FDG-conjugated 2-nitroimidazole derivatives for tumor-hypoxia imaging. Molecular Pharmaceutics, 16: 2118-2128.