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Peking University
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Contact

Email: tuopingluo@pku.edu.cn
Tel: +86-10-62769246
Office: C1018 Chemistry Building
Research Group: http://www.chem.pku.edu.cn/luotp/

Tuoping Luo
Associate Professor of Organic Chemistry

Biography

  • Associate Professor, College of Chemistry and Molecular Engineering, Peking University (2019-now)

  • AssistantProfessor, College of Chemistry and Molecular Engineering, Peking University (2013-2019)

  • Postdoctoral Fellow, H3 Biomedicine, Inc., Cambridge, MA, USA (2011-2013)

  • Ph. D. in Chemistry, Department of Chemistry and Chemical Biology, Harvard University (2005-2011)

  • B.S. in Chemistry, Peking University (2001-2005)


Research Interests

  • Total Synthesis of Bioactive Natural Products

  • Development of New Synthetic Methods

  • Chemical Biology


Teaching

  • Organic Chemistry

  • Intermediate Organic Chemistry

  • Stereochemistry


Awards

  • The 7th CSC-RSC Distinguished Young Investigator Award (2019)

  • Asian Core Program Lectureship Award (2023)


Selected Publications

  1. “Scalable Total Synthesis of (–)-Vinigrol”, Yu, X.; Xiao, L.; Wang, Z.; Luo,T.*J. Am. Chem. Soc. 2019, 141, 3440−3443.

  2. “Total Synthesis of (–)-Oridonin: An Interrupted-Nazarov Approach” Kong, L.†; Su, F.†; Yu, H.; Jiang, Z.; Lu, Y.; Luo, T.*J. Am. Chem. Soc. 2019, 141, 20048−20052.(†co-first author)

  3. “Total Synthesis of (–)-Batrachotoxinin A: A Local-Desymmetrization Approach” Guo, Y.; Guo, Z.; Lu, J.-T.; Fang, R.; Chen, S.-C.; Luo, T.*J. Am. Chem. Soc. 2020, 142,3675−3679.

  4. “Dealkenylative Ni-Catalyzed Cross-Coupling Enabled by Tetrazine and Photoexcitation” Chen, S.-C.; Zhu, Q.; Cao, Y.; Li, C.; Guo, Y.; Kong, L.; Che, J.; Guo, Z.; Chen, H.; Zhang, N.; Fang, X.; Lu, J.-T.; Luo, T.*J. Am. Chem. Soc. 2021, 143, 14046−14052.

  5. “Scalable Total Synthesis of (–)-Triptonide: Serendipitous Discovery of a Visible-Light-Promoted Olefin Coupling Initiated by Metal-Catalyzed Hydrogen Atom Transfer (MHAT)” Fang, X.; Zhang, N.; Chen, S.-C.; Luo, T.*J. Am. Chem. Soc. 2022, 144, 2218−2224.

  6. “Enantioselective Total Syntheses of Grayanane Diterpenoids: (–)-Grayanotoxin III, (+)-Principinol E, and (–)-Rhodomollein XX” Kong, L.; Yu, H.; Deng, M.; Wu, F.; Jiang, Z.; Luo, T.*J. Am. Chem. Soc. 2022, 144, 5268−5273.

  7. “Total Synthesis of (+)-Mutilin: A Transannular [2+2] Cycloaddition/Fragmentation Approach” Chen, H.; Li, Z.; Shao, P.; Yuan, H.; Chen, S.-C.; Luo, T.*J. Am. Chem. Soc. 2022, 144, 15462−15467.

  8. “Enantioselective Total Synthesis of (–)-Zygadenine” Guo, Y.; Lu, J.-T.; Fang, R.; Jiao, Y.; Liu, J.; Luo, T.*J. Am. Chem. Soc. 2023, 145, 20202−20207.

  9. “Photoaffinity Labeling Coupled with Proteomics IdentifyPDI-ADAM17 Module is Targeted by (–)-Vinigrolto Induce TNFR1 Shedding and AmeliorateRheumatoid Arthritis in Mice” Zhu, Y.†; Wang, L.†; Li, J.†; Zhao, Y.; Yu, X.; Liu, P.; Deng, X.; Liu, J.; Yang, F.; Zhang, Y.; Yu, J.; Lai, L.; Wang, C.; Li, Z.*; Wang, L.*; Luo, T.*Cell Chem. Biol. 2024, 31, 452−464. (†co-first author)

  10. “Divergent Syntheses of Complex Veratrum Alkaloids” Guo, Y.†; Fang, R.†; Jiao, Y.†; Liu, J.; Lu, J.-T.; Luo, T.*Nat. Commun. 2024, 15, 7639. (†co-first author)

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