Biography

• Assistant Professor, College of Chemistry and Molecular Engineering, Peking University (2021-now)

• Senior Research Fellow (tenured), Institute for Basic Science, South Korea(2015-2021)

• Ph.D. in Chemistry, University of Arizona (2015)

• B.S. in Chemistry, Beijing Normal University (2009)

Research Interests

• Single-molecule liquid cell electron microscopy, AI-assisted automation and multimodality data analysis. Direct imaging of transient interaction of macromolecules and their critical roles in phase separation, self-assembly and polymerization.

• Boosted diffusion of chemical reaction and emergent phenomenon in nonequilibrium chemical active systems, organized multi-enzymatic systems, and organelles.

Teaching

Quantitative Analytical Chemistry

Awards

• 1st Prize in Peking University Teaching Contest, 2024

• Excellence Fund for Young Scholar, NSFC, 2021

• Best Researcher Award, Institute for Basic Science, 2020

Selected Publications

1. Yu Yuan, Xiaozhe Dong, Huan Wang*, Feng Gai*. Capturing the Illusive Ring-shaped Intermediates in Aβ42 Amyloid Formation. Biophys. Rev. 2024, 5, 032104.

2. Deyi Zhang#, Yi Shao#, Jiayi Zhou, Qiangwei Zhan, Ziyang Wen, Sheng Mao, Jingjing Wei, Limin Qi, Yuanhua Shao*, Huan Wang*. Nanopipette Dynamic Microscopy Unveils Nano Coffee Ring. Proc. Natl. Acad. Sci. U. S. A. 2024, 121, e2314320121.

3. Jia-Ye Li, He Sun, Huan Wang*. lmaging Biomacromolecules in Action with Liquid-Phase Electron Microscopy. Trends Chem. 2024, 6, 281-284.

4. Jia-Ye Li, Zi-Bing Wang, Zhi-Peng Xu, Dong-Dong Xiao, Lin Gu, Huan Wang*. Modes of Nanodroplet Formation and Growth on an Ultrathin Water Film. J. Phys. Chem. B 2024, 128, 3732–3741.

5. Jia-Ye Li#, Fan Liu#, Jing Xu, Ye-Jin Kim, Oh-Hoon Kwon, Bin Xia, Huan Wang*, Steve Granick*. The Ergodicity Question when Imaging DNA Conformation using Liquid Cell Electron Microscopy. Proc. Natl. Acad. Sci. U. S. A. 2024, 121, e2314797121.

6. Bin Cheng, Enze Ye, He Sun*, Huan Wang*. Deep Learning-assisted Analysis of Single Molecule Dynamics from Liquid-phase Electron Microscopy. Chem. Commun. 2023, 59, 1701.

7. Huan Wang#,*, Zhun Xu#, Sheng Mao, Steve Granick*. Experimental Guidelines to Image Transient Single-Molecule Events Using Graphene Liquid Cell Electron Microscopy. ACS Nano 2022, 11, 18526.

8. Tian Huang, Bo Li, Huan Wang*, Steve Granick*. Molecules, the Ultimate Nanomotor: Linking Chemical Reaction Intermediates to their Molecular Diffusivity. ACS Nano 2021, 15, 14947.

9. Huan Wang#, Tian Huang#, Steve Granick*. Using NMR to Test Molecular Mobility during a Chemical Reaction. J. Phys. Chem. Lett. 2021, 12, 2370.

10. Huan Wang, Myeonggon Park, Ruoyu Dong, Junyoung Kim, Yoon-Kyoung Cho, Tsvi Tlusty, Steve Granick*. Boosted Molecular Mobility during Common Chemical Reactions. Science 2020, 369, 537-541.