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Yang Zheng

Yang Group Admin


Changjiang Professor of Chemistry
Department of Chemistry
Peking University

1989-1992Ph.D., Chemistry, The Chinese University of Hong Kong,with Professor Henry N. C. Wong
1983-1986M.S., Pharmaceutical Chemistry, Shenyang College of Pharmacy,with Professor Qihuai Chen
1978-1982B.S., Pharmaceutical Chemistry, Shenyang College of Pharmacy
2002-Changjiang Professor of Chemistry, Dept. of Chemistry, Peking University
2005-2008Director of Chemistry, XTL biopharmaceutical Inc. NY
2001-2005Co-founders and Director of Chemistry, VivoQuest Inc. NY
1998-2001Institute Fellow, Dept. of Cell biology, Harvard Medical School
1995-1998Assistant professor, Dept. of Chemistry, The Scripps Institute
1992-1995Postdoctoral Fellow, Dept. of Chemistry, The Scripps Research Institute, with Professor K. C. Nicolaou
2000The National Science Fund for Distinguished Young Investigator Award (abroad),NSF of China;
2004The National Science Fund for Distinguished Young Investigator Award, NSF of China;
2005Eli Lilly Scientific Excellence Award (China);
2008The Asian Core Program Lectureship Award, the Asian Cutting-Edge Organic Chemistry programs;
2009Baogang Distinguished Teaching Award of Peking University;
2010Wuxi Pharma Life Science Excellence Award (Golden Metal)
2007Advisory Board, Chinese Journal of Organic Chemistry
2010Advisory Board, Combinatorial Science of ACS
2011Advisory Board, Advanced Synthesis & Catalysis of Wiley-VCH
2011Advisory Board, Natural Products and Bioprospecting of Springer
2011Advisory Board, MedChemComm of RSC Publishing

1. Total Syntheses of Drimane-Type Sesquiterpenoids Enabled by a Gold-Catalyzed
    Tandem Reaction

    H. Shi, L. C. Fang, C. H. Tan, L. L. Shi, W. B. Zhang, C. C. Li, T. P. Luo, Yang, Z.
    J. Am. Chem. Soc. 2011, 132, ASAP.

2. Diastereoselective Total Synthesis of (±)-Schindilactone A
    Q. Xiao, W. W. Ren, Z. X. Chen, T. W. Sun, Y. Li, Q. D. Ye, J. X. Gong, F. K. Meng, L.
    You, Y. F. Liu, M. Z. Zhao, L. M. Xu, Z. H. Shan, Y. Shi, Y. F. Tang, J. H. Chen, Yang, Z.
    Angew. Chem. Int. Ed. 2011, 50, 7373.

3. Formal Synthesis of Cortistatins
    L. C. Fang, Y. Chen, J. Huang, L. Z. Liu, J. M. Quan, C. C. Li, Yang, Z.  
    J. Org. Chem. 2011, 76, 2479.

4. A Concise Approach for the Total Synthesis of Pseudolaric Acid A
    T. Xu, C. C. Li, Yang, Z.
    Org. Lett. 2011, 13, 2630.

5. Asymmetric Total Synthesis and Structural Elucidation of NFAT-68
    L. Wang, Y. M. Xi, S. L. Yang, R. Zhu, Y. F. Liang, J. H. Chen, Yang, Z.
    Org. Lett. 2011, 13, 74.

6. Total Synthesis of Maoecrystal V
    Gong, J.; Lin, G.; Sun, W.; Li, C.-C.; Yang, Z.
    J. Am. Chem. Soc., 2010, 132, 16745.

7. Asymmetric Total Synthesis of Caribenol A
    Liu, L.; Han, J.; Yue, G.; Li, C.-C.; Yang, Z.
    J. Am. Chem. Soc., 2010, 132, 13608.

8. A model study for the concise construction of the oxapentacyclic core of  cortistatins
    through intramolecular Diels-Alder and oxidative dearomatization-cyclization reaction

    Liu, L. Z.; Gao, Y. X.; Che, C.; Wu, N.; Wang, D. Z.; Li, C. C.;Yang, Z
    Chemical Communications 2009, 662-664.

9. Total synthesis of crisamicin A
    Li, Z. T.; Gao, Y. X.; Tang, Y. F.; Dai, M. J.; Wang, G. X.; Wang, Z. G.; Yang, Z.
    Org. Lett. 2008, 10, 3017-3020.

10. Diversity-Oriented Synthesis of Fused Pyran gamma-Lactones via an  Efficient Pd-
      Thiourea-Catalyzed Alkoxycarbonylative Annulation

      Li, Z. T.; Gao, Y. X.; Jiao, Z. D.; Wu, N.; Wang, D. Z.; Yang, Z.
      Org. Lett. 2008, 10, 5163-5166.

11. A One-Pot Synthesis of Quinoline-based Tetracycles by a Tandem Three-Component

      Che, C.; Xiang, J.; Wang, G. X.; Quan, J.-M.; Yang, Z.
      J. Comb. Chem. 2007, 9, 982.

12. Development of a Concise and Diversity-Oriented Approach for the Synthesis of
      Plecomacrolides via the Diene-Ene RCM

      Lu, K.; Huang, M.; Xiang, Z.; Liu, Y.; Chen, J.; Yang, Z.
      Org. Lett. 2006, 8, 1193.

13. Synthetic Study of 1,3-Butadiene-Based IMDA Approach to Construct a [5-7-6]
      Tricyclic Core and Its Application to the Total Synthesis of C8-epi-Guanacastepene O

      Li, C. ; Wang, C. ; Liang, B. ; Zhang, X. ; Deng, L. ; Liang, S. ; Chen, J. ; Wu, Y. ;
      Yang, Z

      J. Org. Chem. 2006, 71, 6892.

14. Thioureas as Ligands in the Pd-Catalyzed Intramolecular Pauson-Khand Reaction
      Tang, Y.; Deng, L.; Zhang, Y.; Dong, G.; Chen, J.; Yang, Z
      Org. Lett. 2005, 7, 1657.

15. A Highly Efficient Synthesis of the FGH Ring of Micrandilactone A. Application of
      Thioureas as Ligands in the Co-catalyzed Pauson-Khand Reaction and Pd-Catalyzed
      Carbonylative Annulation

      Tang, Y.; Zhang, Y.; Dai, M.; Luo, T.; Deng, L.; Chen, J.; Yang, Z.
      Org. Lett. 2005, 7, 885-888.

16. Total synthesis of Brevetoxin A
      Nicolaou, K. C.; Yang, Z.; Shi, G.-Q.; Gunzner, J. L.; Agrios, K. A.; Garttner, P.  
      Nature 1998, 392, 264-269.

17. Total synthesis of Taxol
      Nicolaou, K.C.; Yang, Z.; Liu, J.-J.; Ueno, H.; Nantermet, P.G.; Guy, R.K.; Claiborne, 
      C.F.; Renaud, J.; Couladouros, E.A.;   Paulvannan,K.; Sorensen, E.J.

      Nature, 1994, 367, 630-634.

 For full publications see CV (PDF)