2004 2005 2006
2007 2008
2009 2010 2011
2012 2013
2014 2015 2016

# 086

Programmed Selective sp2 C–O Bond Activation toward Multiarylated Benzenes

Fei Zhao, Yun-Fei Zhang, Jing Wen, Da-Gang Yu, Jiang-Bo Wei, Zhen-Feng Xi and Zhang-Jie Shi

Org. Lett., 2013, ASAP <DOI: 10.1021/ol4011757 >


# 085

Benzofuran Synthesis via Copper-Mediated Oxidative Annulation of Phenols and Unactivated Internal Alkynes

Zhang-Jie Shi, Ru-Yi Zhu and Jiang-Bo Wei

Chem. Sci., 2013, Accepted Manuscript<DOI: 10.1039/C3SC51489G >


# 084

Transition-metal-free cross-dehydrogenative alkylation of pyridines under neutral conditions

Xin Li, Hao-Yuan Wang and Zhang-Jie Shi

New J. Chem., 2013, Advance Article <DOI: 10.1039/C3NJ00095H >

# 083

Asymmetric Allylic Alkylation of Alkene through Direct C (sp3)-H Functionalization

G.-H. Chen, K. Chen, Z.-J. Shi

ChemCatChem 2013, 5, 1289–1290 < DOI: 10.1002/cctc.201300015 >

# 082

Asymmetric Allylic Alkylation of Alkene through Direct C (sp3)-H Functionalization

G.-H. Chen, K. Chen, Z.-J. Shi

ChemCatChem 2013, Earyl View < DOI: 10.1002/cctc.201300015 >

# 081

Synthesis and screening of 3-MA derivatives for autophagy inhibitors.

Y.-Y. Wu, X. Wang, H.-J. Guo, B. Zhang, X.-B. Zhang, Z.-J. Shi, L. Yu

Autophagy 2013, 9, 595-603 < DOI: 10.4161/auto.23641 >

# 080

A conceptual translation of homogeneous catalysis into heterogeneous catalysis: homogeneous-like heterogeneous gold nanoparticle catalyst induced by ceria supporter

Z.-X. Li, W. Xue, B.-T. Guan, F.-B. Shi, Z.-J. Shi, H. Jiang, C.-H. Yan

Nanoscale 2013, 5, 1213-1220< DOI: 10.1039/C2NR33011C >

# 079

Cross coupling of thioethers with aryl boroxines to construct biaryls via Rh catalyzed C–S activation.

F. Pan , H. Wang , P.-X. Shen , J. Zhao, Z.-J. Shi

Chem. Sci. 2013, 4, 1573-1577 < DOI: 10.1039/C3SC22242J >

# 078

Direct Lactonization of 2-Arylacetic Acids through Pd(II)-Catalyzed C–H Activation/C–O Formation.

M.-Y. Yang, X.-Y. Jiang, W.-J. Shi, Q.-L. Zhu, Z.-J. Shi

Org. Lett. 2013, 15, 690–693 < DOI: 10.1021/ol303569b >

# 077

Rhodium(I)-Catalyzed Redox-Economic Cross-Coupling of Carboxylic Acids with Arenes Directed by N-Containing Groups.

F. Pan, Z.-Q. Lei, H. Wang, H. Li, J. Sun, Z.-J. Shi

Angew. Chem. Int. Ed. 2013, 52, 2063–2067 < DOI: 10.1002/anie.201208362 >

# 076

Palladium-Catalyzed Trifluoromethylation of Aromatic C–H bond Directed by an Acetamino Group.

L.-S. Zhang, K. Chen, G.-H. Chen, B.-J. Li, S. Luo, Q.-Y. Guo, J.-B. Wei, Z.-J. Shi

Org. Lett. 2013, 15, 10–13 < DOI: 10.1021/ol302814x >

# 075

Transition Metal-Catalyzed C—H Trifluoromethylation

F. Pan, Z.-J. Shi

Acta Chim. Sinica 2012, 70, 1679 < DOI: 10.6023/A12040135 >

# 074

Rh-Catalyzed C-C Cleavage of Benzyl/Allylic Alcohols to Produce Benzyl/Allylic Amines or other Alcohols by Nucleophilic Addition of Intermediate Rhodacycles to Aldehydes and Imines

X.-S. Zhang, Y. Li, H. Li, K. Chen, Z.-Q. Lei, Z.-J. Shi

Chem. Eur. J. 2012, 50, 16214-16225 < DOI: 10.1002/chem.201201867 >

# 073

From C(sp2)–H to C(sp3)–H: systematic studies on transition metal-catalyzed oxidative C–C formation

B.-J. Li, Z.-J. Shi

Chem. Soc. Rev. 2012, 41, 5588-5598 < DOI: 10.1039/C2CS35096C >

# 072

Synthesis of Fluorenone Derivatives through Pd-Catalyzed Dehydrogenative Cyclization

H. Li, R.-Y. Zhu, W. -J. Shi, K.-H. He, Z.-J. Shi

Org. Lett. 2012, 14, 4850–4853. < DOI: 10.1021/ol302181z >

# 071

Reductive Cleavage of the Csp2-Csp3 Bond of Secondary Benzyl Alcohols: Rhodium Catalysis Directed by N-Containing Groups

K. Chen, H. Li, Z.-Q. Lei, Y. Li, W.-H. Ye, L.-S. Zhang, J. Sun, Z.-J. Shi

Angew. Chem. Int. Ed. 2012, 51, 9851–9855. < DOI: 10.1002/anie.201204338 >

# 070

Direct Arylation/Alkylation/Magnesiation of Benzyl Alcohols in the Presence of Grignard Reagents via Ni-, Fe-, or Co-Catalyzed sp3 C–O Bond Activation

D.-G. Yu, X. Wang, R.-Y. Zhu, S. Luo, X.-B. Zhang, B.-Q. Wang, Z.-J. Shi

J. Am. Chem. Soc. 2012, 134, 14638–14641. < DOI: 10.1021/ja307045r >

# 069

Olefinic C–H Bond Addition to Aryl Aldehyde and Its N-Sulfonylimine via Rh Catalysis

Y. Li, X.-S. Zhang, Q.-L. Zhu, Z.-J. Shi

Org. Lett. 2012, 14, 4498–4501. < DOI: 10.1021/ol301989n >


# 068

Challenges in C–C bond formation through direct transformations of sp2 C–H bonds

D.-G. Yu, B.-J. Li, Z.-J. Shi

Tetrahedron 2012, 68, 5130-5136. < DOI: 10.1016/j.tet.2012.05.040 >

# 067

Mechanistic Insight into the Regioselective Palladation of Indole Derivatives: Tetranuclear Indolyl Palladacycles with High C2–Pd or C3–Pd Bond Selectivity

Y. Li, W.-H. Wang, K.-H. He, Z.-J. Shi

Organometallics 2012, 31, 4397-4400. < DOI: 10.1021/om300284t >

# 066

Straightforward synthesis of phenanthrenes from styrenes and arenes

H. Li, K.-H. He, J. Liu, B.-Q. Wang, K.-Q. Zhao, Z.-J. Shi

Chem. Commun. 2012, 48, 7028-7030. < DOI: 10.1039/C2CC33100D >

# 065

Rhodium/Copper-Catalyzed Annulation of Benzimides with Internal Alkynes: Indenone Synthesis through Sequential C-H and C-N Cleavage.

B.-J. Li, H.-Y. Wang, Q.-L. Zhu; Z.-J. Shi

Angew. Chem. Int. Ed. 2012, 51, 3948–3952. < DOI: 10.1002/anie.201200271 >

# 064

Direct Oxidative Arylation via Rhodium-Catalyzed C—C Bond Cleavage of Secondary Alcohols with Arylsilanes.

K. Chen, H. Li, Y. Li, X.-S. Zhang, Z.-Q. Lei; Z.-J. Shi

Chem. Sci. 2012, 3, 1645-1649. < DOI: 10.1039/C2SC00923D >

# 063

Mechanistic Understanding on Rh-Catalyzed N-Sulfonylaldimines Insertion to Aryl C-H Bonds.

Y. Li, X.-S. Zhang, H. Li, W.-H. Wang, K. Chen, B.-J. Li; Z.-J. Shi

Chem. Sci. 2012, 3, 1634-1639. < DOI: 10.1039/C2SC01081J >

# 062

Extrusion of CO from Aryl Ketones: Rhodium(I)-Catalyzed C-C Bond Cleavage Directed by a Pyridine Group.

Z.-Q. Lei, H. Li, Y. Li, X.-S. Zhang, K. Chen, X. Wang, J. Sun; Z.-J. Shi

Angew. Chem. Int. Ed. 2012, 51, 2690–2694. < DOI: 10.1002/anie.201107136>

# 061

N-Directing Group Assisted Rhodium-Catalyzed Aryl C–H Addition to Aryl Aldehydes.

Y. Li, X.-S. Zhang, K. Chen, K.-H. He, F. Pan, B.-J. Li; Z.-J. Shi

Org. Lett. 2012, 14, 636-639. < DOI: 10.1021/ol2032784 >

# 060

One Stone Two Birds: Construction of Polysubstituted Benzenes from the Same Starting Material and Precatalyst by Switching the Active Sites of Catalyst with Different Additives.

C. Feng; X. Wang; B.-Q. Wang; K.-Q. Zhao; P. Hu; Z.-J. Shi

Chem. Commun. 2012, 48, 356-358. < DOI: 10.1039/C1CC15835J >

# 059

Synthesis of Decahydropyrrolo[2,1,5-cd]indolizine through Consecutive [2 + 3] Cycloadditions and 6-Exo-Trig Cyclization.

P.-P. Cui; L. Xu; Z.-J. Shi; L.-B. Gan

J. Org. Chem. 2011, 76, 4210–4212. < DOI: 10.1021/jo200601y >

# 058

Construction of Substituted Benzene Rings by Palladium-Catalyzed Direct Cross-Coupling of Olefins: A Rapid Synthetic Route to 1,4-Naphthoquinone and Its Derivatives.

P. Gu; S. Huang; J. Xu; Z.-J. Shi; W.-P. Su

Angew. Chem. Int. Ed. 2011, 50, 9926-9930. < DOI: 10.1002/anie.201103380 >

# 057

Cross-coupling of Aryl/Alkenyl Silyl Ethers with Grignard Reagents through Nickel-catalyzed C–O Bond Activation.

F. Zhao; D.-G. Yu; R.-Y. Zhu; Z.-F. Xi; Z.-J. Shi

Chem. Lett. 2011, 40, 1001-1003. < DOI: 10.1246/cl.2011.1001 >

# 056

Pyridinyl Directed Alkenylation with Olefins via Rh(III)-Catalyzed C–C Bond Cleavage of Secondary Arylmethanols.

H. Li; Y. Li; X.-S. Zhang; K. Chen; X. Wang; Z.-J. Shi

J. Am. Chem. Soc. 2011, 133, 15244-15247. < DOI: 10.1021/ja205228y >

# 055

Direct Arylation of Alkenes with Aryl Iodides/Bromides through an Organocatalytic Radical Process.

C.-L. Sun, Y.-F. Gu, B. Wang, Z.-J. Shi

Chem. Eur. J. 2011, 17, 10844-10847. < DOI: 10.1002/chem.201101562 >

# 054

Neocuproine-KOtBu Promoted Intramolecular Cross Coupling to Approach Fused Rings.

C.-L. Sun, Y.-F. Gu, W.-P. Huang, Z.-J. Shi

Chem. Commun. 2011, 47, 9813-9815. < DOI: 10.1039/C1CC13907J >

# 053

Mutual Activation: Suzuki-Miyaura Coupling through Direct Cleavage of the sp2 C-O Bond of Naphtholate.

D.-G. Yu, Z.-J. Shi

Angew. Chem. Int. Ed. 2011, 50, 7097-7100. < DOI: 10.1002/anie.201101461 >


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# 052

Arylation of Alfa-Pivaloxyl Ketones with Arylboronic Reagents via Ni-Catalyzed sp3 C-O Activation.

K. Huang, G. Li, W.-P. Huang, D.-G. Yu, Z.-J. Shi

Chem. Commun. 2011, 47, 7224-7226. < DOI: 10.1039/C1CC11193K >

# 051

Direct Sequential C-O and C-C Formation via Double sp2 C-H Bond Activations to Construct 6H-Benzo[c]chromen-6-ones.

C.-L. Sun, J. Liu, Y. Wang, X. Zhou, B.-J. Li, Z.-J. Shi

Synlett 2011, 7, 883-886. < DOI: 10.1055/s-0030-1259724 >

# 050

Transition-Metal-Catalyzed C–C Bond Formation through the Fixation of Carbon Dioxide.

K. Huang, C.-L. Sun, Z.-J. Shi

Chem. Soc. Rev. 2011, 40, 2435-2452. < DOI: 10.1039/C0CS00129E >

# 049

The Catalytic Ability of Various Transition Metals in the Direct Functionalization of Aromatic C-H Bonds.

H. Li, C.-L. Sun, M. Yu, D.-G. Yu, B.-J. Li, Z.-J. Shi

Chem. Eur. J. 2011, 16, 3593-3597. < DOI: 10.1002/chem.201002309 >

# 048

Challenge and Progress: Palladium-Catalyzed sp3 C-H Activation.

H. Li, B.-J. Li, Z.-J. Shi

Catal. Sci. Technol. 2011, 1, 191-206. < DOI: 10.1039/C0CY00076K >

Top Ten

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in October!


# 047

Rhodium-Catalyzed Direct Addition of Aryl C-H Bonds to N-Sulfonyl Aldimines.

Y. Li, B.-J. Li, W.-H. Wang, W.-P. Huang, X.-S. Zhang, K. Chen, Z.-J. Shi

Angew. Chem. Int. Ed. 2011, 50, 2115-2119. < DOI: 10.1002/anie.201007464 >

# 046

Activation of "Inert" Alkenyl/Aryl C-O Bond and Its Application in Cross-Coupling Reactions.

B.-J. Li, D.-G. Yu, C.-L. Sun, Z.-J. Shi

Chem. Eur. J. 2011, 17, 1728-1759. < DOI: 10.1002/chem.201002273 >

# 045

Direct Cross-Coupling of C-H Bonds with Grignard Reagents through Cobalt Catalysis.

B. Li, Z.-H. Wu, Y.-F. Gu, C.-L. Sun, B.-Q. Wang, Z.-J. Shi

Angew. Chem. Int. Ed. 2011, 50, 1109-1113. < DOI: 10.1002/anie.201005394 >


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# 044

Ir-Catalyzed Highly Selective Addition of Pyridyl C–H Bonds to Aldehydes Promoted by Triethylsilane.

B.-J. Li, Z.-J. Shi

Chem. Sci. 2011, 2, 488-493. < DOI: 10.1039/C0SC00419G >

# 043

Dierct C-H Transformation via Iron Catalysis.

C.-L. Sun, B.-J. Li, Z.-J. Shi

Chem. Rev. 2011, 111, 1293-1314. < DOI: 10.1021/cr100198w >

# 042

New Strategy to Construct Fused/Bridged/Spiro Carbocyclic Scaffolds Based on the Design of Novel 6-C Synthon Precursor.

J. Liu, X. Wang, C.-L. Sun, B.-J. Li, Z.-J. Shi, M. Wang

Org. Biomol. Chem. 2011, 9, 1572-1577. < DOI: 10.1039/C0OB00660B >

# 041

Borylation of Aryl and Alkenyl Carbamates through Ni-Catalyzed C-O Activation.

K. Huang, D.-G. Yu, S.-F. Zheng, Z.-H. Wu, Z.-J. Shi

Chem. Eur. J. 2011, 17, 786–791. < DOI: 10.1002/chem.201001943 >

# 040

Palladium-Catalyzed Cross-Coupling of Polyfluoroarenes with Simple Arenes.

H. Li, J. Liu, C.-L. Sun, B.-J. Li, Z.-J. Shi

Org. Lett. 2011, 13, 276–279. < DOI: 10.1021/ol102688e >


# 039

Topics in Current Chemistry: C-H Activation.

J.-Q.Yu, Z.-J. Shi

Springer 2010, 292 < ISBN: 978-3-642-12356-6 >

# 038

An unexpected palladium migration from vinylic sp2 carbon to allylic sp3 carbon.

B.-J.Li, Z.-J. Shi

Chin. Sci. Bull. 2010, 55, 2807-2810. < DOI: 10.1007/11434-010-4034-2 >

# 037

LiCl-Promoted Pd(II)-Catalyzed ortho Carbonylation of N,N-Dimethylbenzylamines.

H. Li, G.-C. Cai, Z.-J. Shi

Dalton Trans. 2010, 39, 10442-10446. < DOI: 10.1039/C0DT00451K >

# 036

An Efficient Organocatalytic Method for Constructing Biaryls through Aromatic C-H Activation.

C.-L. Sun, H. Li, D.-G. Yu, M. Yu, X. Zhou, X.-Y. Lu, K. Huang, S.-F. Zheng, B.-J. Li, Z.-J. Shi

Nat. Chem. 2010, 2, 1044-1049. < DOI: 10.1038/nchem.862 >


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# 035

Exploration of New C-O Electrophiles in Cross-Coupling Reactions.

D.-G. Yu, B.-J. Li, Z.-J. Shi

Acc. Chem. Res. 2010, 43, 1486–1495. < DOI: 10.1021/ar100082d >

Most Accessed Articles 2010


# 034

Oxidative Dimerization of N-Protected and Free Indole Derivatives toward 3,3'-Biindoles via Pd-Catalyzed Direct C-H Transformations.

Y. Li , W.-H. Wang, S.-D. Yang, B.-J. Li, C. Feng, Z.-J. Shi

Chem. Commun. 2010, 46, 4553-4555. < DOI: 10.1039/C0CC00486C >

# 033

Direct Application of Phenolic Salts to Nickel-Catalyzed Cross-Coupling Reactions with Aryl Grignard Reagents.

D.-G. Yu, B.-J. Li, S.-F. Zheng, B.-T. Guan, B.-Q. Wang, Z.-J. Shi

Angew. Chem. Int. Ed. 2010, 49, 4566-4570. < DOI: 10.1002/anie.200907359 >


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# 032

Construction of Polysubstituted Olefins through Ni-Catalyzed Direct Activation of Alkenyl C-O of Substituted Alkenyl Acetates.

C.-L. Sun, Y. Wang, X. Zhou, Z.-H. Wu, B.-J. Li, B.-T. Guan, Z.-J. Shi

Chem. Eur. J. 2010, 16, 5844-5847. < DOI: 10.1002/chem.200902785 >


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# 031

Nickel-Catalyzed Efficient and Practical Suzuki-Miyaura Coupling of Alkenyl and Aryl Carbamates with Aryl Boroxines.

L. Xu, B.-J. Li, Z.-H. Wu, X.-Y. Lu, B.-T. Guan, B.-Q. Wang, K.-Q. Zhao, Z.-J. Shi

Org. Lett. 2010, 12, 884-887. < DOI: 10.1021/ol9029534 >


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# 030

Pd-Catalyzed Oxidative Coupling with Organometallic Reagents via C-H Activation.

C.-L. Sun, B.-J. Li, Z.-J. Shi

Chem. Commun. 2010, 46, 677-685. < DOI: 10.1039/B908581E >

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# 029

Pd-Catalyzed C-H Functionalizations of O-Methyl Oximes with Arylboronic Acids.

C.-L. Sun, N. Liu, B.-J. Li, D.-G. Yu, Y. Wang, Z.-J. Shi

Org. Lett. 2010, 12, 184-187. < DOI: 10.1021/ol902552v >

# 028

Macrolactones and Macrolactams.

C.-L. Sun, B.-J. Li, Z.-J. Shi

Handbook of Cyclization Reactions. 2010, 2, 1055-1097. < ISBN: 978-3-527-32088-2 >

# 027

Biaryl Construction through Kumada Coupling with Diaryl Sulfates as One-by-One Electrophiles under Mild Conditions.

B.-T. Guan, X.-Y. Lu, Y. Zheng, D.-G. Yu, T. Wu, K.-L. Li, B.-J. Li, Z.-J. Shi

Org. Lett. 2010, 12, 396-399. < DOI: 10.1021/ol9028308 >


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# 026

Organopalladium(IV) Chemistry.

L.-M. Xu, B.-J. Li, Z. Yang, Z.-J. Shi

Chem. Soc. Rev. 2010, 39, 712-733. < DOI: 10.1039/B809912J >


# 025

Direct Functionalization of Benzylic C–Hs with Vinyl Acetates via Fe-Catalysis.

C.-X. Song, G.-X. Cai, T. R. Farrell, Z.-P. Jiang, H. Li, L.-B. Gan, Z.-J. Shi

Chem. Commun. 2009, 6002-6004. < DOI: 10.1039/B911031C >

# 024

Cross-Coupling of Alkenyl/Aryl Carboxylates with Grignard Reagent via Fe-Catalyzed C-O Bond Activation.

B.-J. Li, L. Xu, Z.-H. Wu, B.-T. Guan, C.-L. Sun, B.-Q. Wang, Z.-J. Shi

J. Am. Chem. Soc. 2009, 131, 14656-14657. < DOI: 10.1021/ja907281f >


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# 023

Carbon-Carbon Formation via Ni-Catalyzed Suzuki-Miyaura Coupling through C-CN Bond Cleavage of Aryl Nitrile.

D.-G. Yu, M. Yu, B.-T. Guan, B.-J. Li, Y. Zheng, Z.-H. Wu, Z.-J. Shi

Org. Lett. 2009, 11, 3374-3377. < DOI: 10.1021/ol901217m >


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# 022

Direct Imidation to Construct 1H-Benzo[d]imidazole through Pd(II)-Catalyzed C-H Activation Promoted by Thiourea.

Q. Xiao, W. Wang, G. Liu, F. Meng, J. Chen, Z. Yang, Z. Shi

Chem. Eur. J. 2009, 15, 7292-7296. < DOI: 10.1002/chem.200900154 >

# 021

Cross Dehydrogenative Arylation (CDA) of a Benzylic C-H Bond with Arenes by Iron Catalysis.

Y. Li, B. Li, X. Lu, S. Lin, Z. Shi

Angew. Chem. Int. Ed. 2009, 48, 3817-3820. < DOI: 10.1002/anie.200900341 >

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# 020

Gold-Catalyzed Benzylic Oxidation to Carbonyl Compounds.

H. Li, Z. Li, Z. Shi

Tetrahedron 2009, 65, 1856-1858. < DOI: 10.1016/j.tet.2008.12.055 >



# 019

China: In their words.

Foster collaboration. Zhang-Jie Shi*.

Nature 2008,454, 399-402. < DOI: 10.1038/454399a >

# 018

A small molecule enhances RNA interference and promotes microRNA processing.

G. Shan, Y. Li, J. Zhang, W. Li, K. E. Szulwach, R. Duan, M. A. Faghihi, A. M. Khalil, L. Lu, Z. Paroo, A. W. S. Chan, Z.-J. Shi, Q. Liu, C. Wahlestedt, C. He, P. Jin

Nature Biotechnology 2008, 26, 933-940. < DOI: 10.1038/nbt.1481 >

# 017

Cross-Coupling of Aryl/Alkenyl Pivalates with Organozinc Reagents through Nickel-Catalyzed C-O Bond Activation under Mild Reaction Conditions.

B. Li, Y. Li, X. Lu, J. Liu, B. Guan, Z. Shi

Angew. Chem. Int. Ed. 2008, 47, 10124-10127. < DOI: 10.1002/anie.200803814 >


Research Highlight

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# 016

Intra/Intermolecular Direct Allylic Alkylation via Pd(II)-Catalyzed Allylic C-H Activation.

S. Lin, C. Song, G. Cai, W. Wang, Z. Shi

J. Am. Chem. Soc. 2008, 130, 12901-12903. < DOI: 10.1021/ja803452p >

Research Highlight

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# 015

Biaryl Construction via Ni-Catalyzed C-O Activation of Phenolic Carboxylates.

B. Guan, Y. Wang, B. Li, D. Yu, Z. Shi

J. Am. Chem. Soc. 2008, 130, 14468-14470. < DOI: 10.1021/ja8056503 >

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# 014

Direct Benzylic Alkylation via Ni-Catalyzed Selective Benzylic sp3 C-O Activation.

B.-T. Guan, S.-K. Xiang, B.-Q. Wang, Z.-P. Sun, Y. Wang, K.-Q. Zhao, Z.-J. Shi

J. Am. Chem. Soc. 2008, 130, 3268-3269. < DOI: 10.1021/ja710944j >

# 013

Methylation of Arenes via Ni-Catalyzed Aryl C-O/F Activation.

B. Guan, S. Xiang, T. Wu, Z. Sun, B. Wang, K. Zhao, Z. Shi

Chem. Commun. 2008, 12, 1437-1439. < DOI: 10.1039/B718998B >

# 012

Recent Advances in Direct Arylation via Palladium-Catalyzed Aromatic C-H Activation.

B. Li, S. Yang, Z. Shi

Synlett. 2008, 7, 949-957. < DOI: 10.1055/s-2008-1042907 >

# 011

Benzylation of Arenes through FeCl3-Catalyzed Friedel-Crafts Reaction via C-O Activation of Benzyl Ether.

B. Wang, S. Xiang, Z. Sun, B. Guan, P. Hu, K. Zhao, Z. Shi

Tetrahedron Lett 2008, 49, 4310-4312. < DOI: 10.1016/j.tetlet.2008.04.117 >

# 010

Palladium-Catalyzed Direct Arylation of (Hetero)Arenes with Aryl Boronic Acids.

S. Yang, C. Sun, Z. Fang, B. Li, Y. Li, Z. Shi

Angew. Chem. Int. Ed. 2008, 47, 1473-1476. < DOI: 10.1002/anie.200704619 >


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# 009

Multiple C-H Activations to Construct Biologically Active Molecules in a Process Completely Free of Organohalogen and Organometallic Components.

B. Li, S. Tian, Z. Fang, Z. Shi

Angew. Chem. Int. Ed. 2008, 47, 1115-1118. < DOI: 10.1002/anie.200704092 >


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# 008

Suzuki-Miyaura Coupling Reaction by Pd(II)-Catalyzed Aromatic C-H Bond Activation Directed by an N-Alkyl Acetamino Group.

Z. Shi, B. Li, X. Wan, J. Cheng, Z. Fang, B. Cao, C. Qin, Y. Wang

Angew. Chem. Int. Ed. 2007, 46, 5554-5558. < DOI: 10.1002/anie.200700590 >

Research Highlight

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# 007

Indirect ortho Functionalization of Substituted Toluenes through ortho Olefination of N,N-Dimethylbenzylamines Tuned by the Acidity of Reaction Conditions.

G. Cai, Y. Fu, Y. Li, X. Wan, Z. Shi

J. Am. Chem. Soc. 2007, 129, 7666-7673. < DOI: 10.1021/ja070588a >

# 006

Aerobic Oxidation of Alcohol in Aqueous Solution Catalyzed by Gold.

H. Li, B. Guan, W. Wang, D. Xing, Z. Fang, X. Wan, L. Yang, Z. Shi

Tetrahedron 2007, 63, 8430-8434. < DOI: 10.1016/j.tet.2007.05.117 >

# 005

Ortho Arylation of Acetanilides via Pd(II)-Catalyzed C-H Functionalization.

S. Yang, B. Li, X. Wan, Z. Shi

J. Am. Chem. Soc. 2007, 129, 6066-6067. < DOI: 10.1021/ja070767s >


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# 004

Multiple Peprotonations and Deaminations of Phenethylamines to Synthesize Pyrroles.

X. Wan, D. Xing, Z. Fang, B. Li, F. Zhao, K. Zhang, L. Yang, Z. Shi

J. Am. Chem. Soc. 2006, 128, 12046-12047. < DOI: 10.1021/ja061176p >


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# 003

Highly Selective C-H Functionalization/Halogenation of Acetanilide.

X. Wan, Z. Ma, B. Li, K. Zhang, S. Cao, S. Zhang, Z. Shi

J. Am. Chem. Soc. 2006, 128, 7416-7417. < DOI: 10.1021/ja060232j >

# 002

Gold(I)-Catalyzed Oxidative Cleavage of a C-C Double Bond in Water.

D. Xing, B. Guan, G. Cai, Z. Fang, L. Yang, Z. Shi

Org. Lett. 2006,8, 693-696. < DOI: 10.1021/ol052830t >

Most Accessed Articles 2006 more >>


# 001

Highly Selective Aerobic Oxidation of Alcohol Catalyzed by a Gold(I) Complex with an Anionic Ligand.

B. Guan, D. Xing, G. Cai, X. Wan, N. Yu, Z. Fang, L. Yang, Z. Shi

J. Am. Chem. Soc. 2005, 127, 18004-18005. < DOI: 10.1021/ja055398j >




Intramolecular Additions of Alcohols and Carboxylic Acids to Inert Olefins Catalyzed by Silver(I) Triflate.

C.-G. Yang, N. W. Reich, Z. Shi, C. He, Org. Lett. 2005, 7, 4553-4556.


Direct Functionalization of Arenes by Primary Alcohol Sulfonate Esters Catalyzed by Gold(III).

Z. Shi, C. He, J. Am. Chem. Soc. 2004, 126, 13596-13597.

Efficient Functionalization of Aromatic C–H Bonds catalyzed by Gold(III) under Mild and Solvent Free Conditions.

Z. Shi, C. He, J. Org. Chem. 2004, 69, 3669-3671.

An Au-Catalyzed Cycloalkylation of Electron-Rich Arenes with Epoxides to Prepare 3-Chromanols.

Z. Shi, C. He, J. Am. Chem. Soc. 2004, 126, 5964-5965.

Design and Synthesis of New Triazo-Ligand and Their Complexes.

Z. Shi, C. He, Abstracts of Papers, 228th ACS National Meeting, Philadelphia, PA, 2004, United States of America.

Gold(III)-Catalyzed Electron Rich Aromatic C–H Bonds Functionalization.

Z. Shi, C. He, Abstracts of Papers, 228th ACS National Meeting, Philadelphia, PA, 2004, United States of America.

Aromatic C–H Bonds Functionalization for Addition to Different Electrophiles.

Z. Shi, C. He, Abstracts of Papers, 228th ACS National Meeting, Philadelphia, PA, 2004, United States of America.

An Efficient Synthesis of 4-Halo-5-hydroxyfuran-2(5H)-ones via the Sequential Halolactonization and g-Hydroxylation of 4-Aryl-2,3-alkadienoic Acids.

S. Ma, B. Wu, Z. Shi, J. Org. Chem. 2004, 69, 1429-1431.


Unpredictable Stereochemical Preferences for Mu Opioid Receptor Activity in an Exhaustively Stereodiversified Library of 1,4-Enediols.

Z. Shi, B. A. Harrison, G. L. Verdine, Org. Lett. 2003, 5, 633-636.

Extensively Stereodiversified Scaffolds for Use in Diversity-Oriented Library Synthesis.

T. M. Gierasch, Z. Shi, G. L. Verdine, Org. Lett. 2003, 5, 621-624.


Mechanistic Switch Leading to Highly Efficient Chirality Transfer in Pd (0)-Catalyzed Coupling-Cyclization of Aryl Iodides with 1:1 Acid-Base Salts of 2, 3-Allenoic Acids and l-(-) -Cinchonidine or d-(+)-/l-(-)-a-Methylbenzylamine. Enantioselective Synthesis of Highly Optically Active 3-Aryl Polysubstituted Butenolides.

S. Ma, Z. Shi, Chem. Commun. 2002, 5, 540-541.


Optically Active beta-Aryl Substitution-2(5H)-ketofuran and Its Synthesis Process.

S. Ma, Z. Shi, Faming Zhuanli Shenqing Gongkai Shuomingshu 2001, 8 pp.

Synthesis of 4-Halo-2(5H)-furanones and Their Suzuki-Coupling Reactions with Organoboronic Acids. A General Route to 4-Aryl-2(5H)-furanones.

S. Ma, Z. Shi, Chin. J. Chem. 2001, 19, 1280-1284.

Enantioselective Synthesis of b-Arylbutenolides via Palladium(0) Catalyzed Asymmetric Coupling Cyclization Reaction of Racemic Allenic Carboxylic Acids with Aryl Iodides.

S. Ma, Z. Shi, S. Wu, Tetrahedron: Asymmetry 2001, 12, 193-195.


Palladium(0)-Catalyzed Cyclization Reaction of Polymer-Supported Aryl Iodides with 1,2-Allenyl Carboxylic Acids. A Facile Solid-Phase Synthesis of Butenolides.

S. Ma, D. Duan, Z. Shi, Org. Lett. 2000, 2, 1419-1422.


Synthesis of b-Halobutenolides and Their Pd(0)-Catalyzed Cross-Coupling Reactions with Terminal Alkynes and Organozinc Reagents. A General Route to b-Substituted Butenolides and Formal Synthesis of cis-Whisky Lactone.

S. Ma, Z. Shi, Z. Yu, Tetrahedron 1999, 55, 12137-12148.

Synthesis of b-Halobutenolides and Their Pd(0)/CuI-Catalyzed Cross-Coupling Reactions with Terminal Alkynes. A General Route to b-(1-Alkynyl)butenolides.

S. Ma, Z. Shi, Z. Yu, Tetrahedron Lett. 1999, 40, 2393-2396.


Pd(0)/Ag+-Cocatalyzed Cyclization Reaction of 1,2-Allenic Carboxylic Acids with Aryl/Alkenyl Halides. An Efficient Synthesis of Butenolides.

S. Ma, Z. Shi, J. Org. Chem. 1998, 63, 6387-6389.

Efficient Synthesis of 4-Halo-4-penten-2-ones and 3-Halo-3-butenoic Acids/Esters via Hydrohalogenation Reaction of 3,4-Pentadien-2-one and 2,3-Butadienoic Acid/Methyl Ester.

S. Ma, Z. Shi, L. Li, J. Org. Chem. 1998, 63, 4522-4523.