Welcome to our lab at College of Chemistry and Molecular Engineering, Peking University!
We aim to invent chemical and biophysical tools to probe neuronal structure and activity at high spatial and temporal resolutions. We apply these tools to investigate the underlying physical forces, chemical signaling, and biological macromolecules that give rise to neuronal functions. Examples are fluorescent sensors, engineered enzymes, custom-built microscopes and software, etc.
Our methods are drawing from a wide range of techniques, including Biophysics, Protein engineering, Molecular Biology, Chemical Synthesis, Fluorescence Microscopy and Quantitative Modeling.
Current research projects include:
Our work on hybrid voltage indicator is officially accepted in Angewandte Chemie International Edition ! By site-specifically modifying microbial rhodopsin on live cell surface with organic fluorophores ...
As 2018 approaches, we are delighted to welcome three CCME graduate students to join our group: Yuxin Fang, Shuzhang Liu, and Ruixuan Wang. ...
Congratulations to Yu Wang and three Yuxin's (~ Fang, ~ Mi, ~ Duan) for successfully defending their theses and getting Bachelor's degrees! ...
The past decade has seen a proliferation of fluorescent voltage indicators. ...
We are delighted to have Ruirui Ma and Yuxin Fang joining our group. ...