GROUP PUBLICATIONS

2020

42.Jingyun Ren, Mengxin Xu, Junyi Chen, Jie Ding, Peipei Wang, Li Huo*, Fang Li*, Zhibo Liu*, PET Imaging Facilitates Antibody Screening for Synergistic Radioimmunotherapy with A 177Lu-Labeled αPD-L1 Antibody. Theranostics, accepted with revision.

41.Qunfeng Fu, Hongyu Li, Dongban Duan, Changlun Wang, Huimin Ma, Zhibo Liu*, External Radiation–Induced Local Hydroxylation Enables Remote Release of Functional Molecules in Tumors, Angew. Chem. Int. Ed., accepted with revision.

40.Qinyang Wang, Yupeng Wang, Jingjin Ding, Chunhong Wang, Xuehan Zhou, Wenqing Gao, Huanwei Huang, Feng Shao*, Zhibo Liu*, A Bioorthogonal System Reveals Antitumour Immune Function of Pyroptosis. Nature, 2020, 579, 421–426.

2019

39.Junyi Chen, Cong Li, Hanyu Hong, Hui Liu, Chunhong Wang, Mengxin Xu, Yuxiang Han, Zhibo Liu*, Side Chain Optimization Remarkably Enhances the In Vivo Stability of 18F-Labeled Glutamine for Tumor Imaging. Mol Pharm. 2019,16, 12, 5035–5041.  

38.Qunfeng Fu, Junyi Chen,Zhibo Liu*, Cherenkov Light: A New Light Source for Theranostics With Nano-Drug. J Nucl Radiochem, 2019: 41(2): 201-207.

37.Jiyuan Li, Yaxin Shi, Zizhu Zhang, Hui Liu, Lixin Lang, Tong Liu, Xiaoyuan Chen*, Zhibo Liu*, A Metabolically Stable Boron-Derived Tyrosine Serves as a Theranostic Agent for Positron Emission Tomography Guided Boron Neutron Capture Therapy. Bioconjug Chem, 2019, 30 (11), 2870-2878.

36.Liping Li, Jiyuan Li, Yaxin Shi, Ping Du, Zizhu Zhang, Tong Liu, Ruiping Zhang*, Zhibo Liu*, On-Demand Biodegradable Boron Nitride Nanoparticles for Positron Emission Tomography Guided Boron Neutron Capture Therapy. ACS Nano, 2019, 13 (12), 13843-13852.  

35.Hsiou-Ting Kuo, Mathieu Lepage, Kuo-Shyan Lin, Jinhe Pan, Zhengxing Zhang, Zhibo Liu, Alla Pryyma, Chengcheng Zhang, Helen Merkens, Aron Roxin, David Perrin, Francois Benard One-step 18F-labeling and preclinical evaluation of prostate specific membrane antigen trifluoroborate probes for cancer imaging. J Nucl Med., 2019,in press.

2018

34.Shi, Yaxin; Li, Jiyuan; Zhang, Zizhu; Duan, Dongban; Zhang, Zhengchu; Liu, Hui; Liu, Tong; Liu, Zhibo*, Tracing Boron with Fluorescence and PET Imaging of Boronated Porphyrin Nanocomplex for Imaging Guided Boron Neutron Capture Therapy. ACS Applied Materials & Interfaces, 2018, 10, 50, 43387-43395

33.Dongban Duan, Hui Liu, Mengxin Xu, Mengqi Chen, Yuxiang Han, Yaxin Shi, Zhibo Liu* , Size-Controlled Synthesis of Drug Loaded Zeolitic Imidazolate Framework in Aqueous Solution and Size Impact on Their Cancer Theranostics In Vivo. ACS Applied Materials & Interfaces, 2018, 10(49): 42165-42174.

32.Cong Li, Hui Liu, Dongban Duan, Zhenhan Zhou, Zhibo Liu*, Preclinical Study of An 18F-Labeled Glutamine Derivative for Cancer Imaging. Nucl Med Biol, 2018, 64: 34-40.

31.Mengxin Xu, Yuxiang Han, Guizhong Liu, Yang Xu, Dongban Duan, Hui Liu, Felix Du, Peter Luo, Zhibo Liu*, Preclinical Study of A Fully Human Anti-PD-L1 Antibody as A Theranostic Agent for Cancer Immunotherapy. Mol Pharm, 2018, 15(10): 4426-4433.

30. Dongban Duan, Hui Liu, Yang Xu, Yuxiang Han, Mengxin Xu, Zhengchu Zhang, Zhibo Liu*, Activating TiO2 Nanoparticles: Gallium-68 Serves as a High-Yield Photon Emitter for Cerenkov-Induced Photodynamic Therapy. ACS Appl Mater Interface, 2018, 10, 5278-5286.

29. Hui Liu, Yuxiang Han, Jiyuan Li, Ming Qin, Qunfeng Fu, Chunhong Wang, and Zhibo Liu*, (18)F-Alanine Derivative Serves as an ASCT2 Marker for Cancer Imaging. Mol Pharm, 2018, 15, 947-954.

28. Cong Li, Hui Liu, Yuxiang Han, Zhibo Liu*, Nuclear Medicine: The Synergy of Radiochemistry and Molecular Medicine. University Chemistry, 2018, 33(3): 1-10.

27. Xiangyu Yang, Zhibo Liu, Huimin Zhang, Zhu Li, Jeeva P. Munasinghe, Gang Niu, Gaojun Teng, Xiaoyuan Chen, Preclinical evaluation of an (18)F-trifluoroborate methionine derivative for glioma imaging. Eur J Nucl Med Mol Imaging, 2018, 45, 585-592.

26.Feng Wang, Teli Liu, Liqiang Li, Xiaoyi Guo, Dongban Duan, Zhibo Liu, Hua Zhu, Zhi Yang Production, quality control of next-generation PET radioisotope iodine-124 and its thyroid imaging. J. Radioanal. Nucl. Chem., 2018, 318, 1999–2006.

2010-2017

25. Zhibo Liu*, Xiaoyuan Chen* Simple Bioconjugate Chemistry Serves Great Clinical Advances: Albumin as A Versatile Platform for Diagnosis and Precision Therapy. Chem. Soc. Rev., 2016, 45, 1432-1456 (*Coresponding author)

24. Zhibo Liu*, Haojun Chen, Kai Chen, Yihan Shao, Dale O. Kiesewetter, Gang Niu, Xiaoyuan Chen* Boramino Acid as A Marker for Amino Acid Transporter. Science Advances, 2015;1:e1500694 (*Coresponding author, highlighted on C&EN News)

23. Zhibo Liu*, Kuo-Shyan Lin, François Bénard, Dale O. Kiesewetter, David M. Perrin*, Xiaoyuan Chen* A Broadly Applicable One-step 18F-Labeling Protocol with Organotrifluoroborates. Nat. Protoc., 2015, 10, 1423–1432 (*Coresponding author)

22. Zhibo Liu, Guillaume Amouroux, Zhengxing Zhang, Nadine Colpo, Joseph Lau, David M. Perrin, Jinhe Pan, François Bénard, Navjit Hundal-Jabal, Kuo-Shyan Lin 18F-Trifluoroborate Derivatives of [Des-Arg10]Kallidin for Imaging Bradykinin B1 Receptor Expression with Positron Emission Tomography. Mol. Pharm., 2015, 12, 974-982

21. Zhibo Liu, David M. Perrin, Using Principles of Physical Organic Chemistry to Designing Kinetically Stable Aryltrifluoroborates as 18F-Capture Agents for PET Imaging, J. Phys. Org. Chem., 2015, 28, 210-214

20. Zhibo Liu, Daniel Chao, Ying Li, Richard Ting, Jihyoon Oh, David M. Perrin From Minutes to Years: Predicting Solvolysis Rates for Organotrifluoroborates, Chem. Eur. J., 2015, 21, 3924-3928

19. Zhibo Liu, Maral Pourghiasian, Gemma Dias, Joseph Lau, Francois Benard, Kuo-shyan Lin, David M. Perrin, An Organotrifluoroborate for Broadly Applicable One-Step 18F-Labeling, Angew. Chem. Int. Ed., 2014, 53, 11876–11880 (Cover feature, highlighted on C&EN News)

18. Zhibo Liu, Mark Alex Radtke, May Q. Wong, Kuo-Shyan Lin, Donald Yapp, David M. Perrin, Dual Mode Fluorescent PET Tracers: Efficient modular synthesis of Rhodamine-[cRGD]2-Alkyl-18F-Trifluoroborate, Rapid 18F-labeling at very high specific activity, In vivo PET Imaging, and Ex vivo fluorescence, Bioconjugate Chem. 2014, 25, 1951–1962 (Cover feature)

17. Zhibo Liu, Maral Pourghiasian, Francois Benard, Jinhe Pan, Kuo-Shyan Lin, David M. Perrin, Preclinical Evaluation of A High Affinity 18F-Trifluorborate Octreotide Derivative for Somatostatin Receptor Imaging, J. Nucl. Med., 2014, 55, 1499-1505 (2014 JNM Editor's Choice Award)

16. Zhibo Liu, Navjit Hundal, May Q. Wong, Kuo-Shyan Lin, Donald Yapp, François Bénard, David M. Perrin, A New 18F-Heteroaryltrifluoroborate with Greatly Enhanced Stability That Is Labelled by 18F-19F-Isotope Exchange in Good Yield at High Specific Activity, MedChemComm, 2014, 5, 171–179

15. Zhibo Liu, Ying Li, Jerome Lozada, Paul Schaffer, Michael J. Adam, Thomas J. Ruth, David M. Perrin, Stoichiometric Leverage: Rapid 18F-Aryltrifluoroborate Radiosynthesis at Exceptionally High Specific Activity For Click Conjugation, Angew. Chem. Int. Ed., 2013, 52, 2303-2307.

14. Zhibo Liu, Ying Li, Jerome Lozada, May Q. Wong, Jennifer Greene, Kuo-Shyan Lin, Donald Yapp, David M. Perrin, Kit-like 18F-labeling of RGD-19F-Arytrifluroborate in High Yield and at Extraordinarily High Specific Activity with Preliminary In Vivo Tumor Imaging, Nucl. Med. Biol., 2013, 40, 841-849.

13. Zhibo Liu, Ying Li, Jerome Lozada, Jinhe Pan, Kuo-Shyan Lin, Paul Schaffer, David M. Perrin, Rapid One-Step 18F-Labeling of Aryltrifluoroborate Conjugates by Isotope Exchange at High Specific Activity, J. Labelled Comp. Radiopharm., 2012, 55 491–496.

12. Joseph Lau✝, Zhibo Liu✝, Kuo-Shyan Lin, Jinhe Pan, Zhengxing Zhang, Daniela Vullo, Claudiu T. Supuran, David M. Perrin, François Bénard Trimeric radiofluorinated sulfonamide derivatives to achieve in vivo selectivity for carbonic anhydrase IX-targeted PET imaging, J. Nucl. Med., 2015, 56, 1434-1440

11. Maral Pourghiasian✝, Zhibo Liu✝, David M. Perrin, Jinhe Pan, Kuo-Shyan Lin, Francois Benard, 18F-AmBF3-MJ9: A novel radiofluorinated bombesin derivative for prostate cancer imaging, Bioorg. Med. Chem. Lett., 2015, 23, 1500-1506

10. Jerome Lozada, Zhibo Liu, David M. Perrin, Base-promoted protodeboronation of 2,6-disubstituted arylboronic acids, J. Org. Chem, 2014, 79, 5365-5368

9. Ying Li, Zhibo Liu, Maral Pourghiasian, Kuo-Shyan Lin, Paul Schaffer, Francois Benard, David M. Perrin,Alkynyl-18F-ArBF3 for One-pot Click 18F-Labeling of Demobesin for In Vivo PET Imaging of Tumors Expressing the GRP-Receptor, Am. J. Nucl. Med. Mol. Imaging., 2013, 3, 57-70.

8. Ying Li, Zhibo Liu, May Q. Wong, Kuo-Shyan Lin, Donald T. Yapp, David M. Perrin, One-Step 18F-Labeling of Dimeric CycloRGD at High Specific Activity for Functional PET Imaging of Tumors in Mice, Nucl. Med. Biol., 2013, 40, 959-966

7. Vadim Bernard-Gauthier, Justin J Bailey, Zhibo Liu, Björn Wängler, Carmen Wängler, Klaus Jurkschat, David M Perrin, Ralf Schirrmacher. From Unorthodox to Established: The Current Status of 18F-Trifluoroborate-and 18F-SiFA-Based Radiopharmaceuticals in PET Nuclear Imaging. Bioconjugate Chem., 2016, 27, 267–279

6. Zhengxing Zhang, Silvia Jenni, Chengcheng Zhang, Helen Merkens, Joseph Lau, Zhibo Liu, David M Perrin, François Bénard, Kuo-Shyan Lin Synthesis and evaluation of 18 F-trifluoroborate derivatives of triphenylphosphonium for myocardial perfusion imaging. Bioorg. Med. Chem. Lett., 2016, 26, 1675–1679

5. Joseph Lau, Zhengxing Zhang, Silvia Jenni, Hsiou-Ting Kuo, Zhibo Liu, Daniela Vullo, Claudiu T Supuran, Kuo-Shyan Lin, Francois Benard PET Imaging of Carbonic Anhydrase IX Expression of HT-29 Tumor Xenograft Mice with 68Ga-Labeled Benzenesulfonamides Mol. Pharm., 2016, 13, 1137–1146

4. Guillaume Amouroux, Jinhe Pan, Silvia Jenni, Chengcheng Zhang, Zhengxing Zhang, Navjit Hundal-Jabal, Nadine Colpo, Zhibo Liu, François Bénard, Kuo-Shyan Lin. Imaging Bradykinin B1 Receptor with 68Ga-Labeled [des-Arg10] Kallidin Derivatives: Effect of the Linker on Biodistribution and Tumor Uptake. Mol. Pharmaceutics, 2015, 12, 2879–2888

3. Kuo-Shyan Lin, Guillaume Amouroux, Jinhe Pan, Zhengxing Zhang, Silvia Jenni, Joseph Lau, Zhibo Liu, François Bénard. Comparative Studies of Three 68Ga-Labeled [Des-Arg10] Kallidin Derivatives for Imaging Bradykinin B1 Receptor Expression with PET Imaging. J. Nucl. Med., 2015, 56(4), 622-627

2. Joseph Lau, Jinhe Pan, Zhengxing Zhang, Navjit Hundal-Jabal, Zhibo Liu, François Bénard, Kuo-Shyan Lin. Synthesis and evaluation of 18F-labeled tertiary benzenesulfonamides for imaging carbonic anhydrase IX expression in tumours with positron emission tomography. Bioorg. Med. Chem. Lett., 2014, 24, 3064–3068

1. Jinhe Pan, Joseph Lau, Felix Mesak, Navjit Hundal, Maral Pourghiasian, Zhibo Liu, François Bénard, Shoukat Dedhar, Claudiu T. Supuran, and Kuo-Shyan Lin, Synthesis and evaluation of 18F-labeled carbonic anhydrase IX inhibitors for imaging with positron emission tomography, J. Enzyme. Inhib. Med. Chem., 2014, 29, 249-255