Address: College of Chemistry and Molecular Engineering , Peking University, Beijing 100871, P. R. China;
Phone: 62757196; Fax: 62754127; Email: yliu@pku.edu.cn

Research projects and interests:

1. Biomedical applications of Accelerator Mass Spectrometry (Bio-AMS)
   Study of genotoxcity and assessment of carcinogenesis of small toxic molecules (e.g., nicotine, formic acid, MTBE, acrylamide etc.) by means of measuring DNA-adducts and protein-adducts with toxicants in vivo. Chemical mechanism of adduct formation studied by AMS-HPLC method.
2. Chemical functionalization, biodistribution, toxicity and applications of fullerene, carbon nanotubes
   Functionalization, distribution and toxicity of carbon nanotubes. Functionalization of carbon nanotubes, fullerene and nanocrystals for biosensor and tumor targeting.

Current Academic Positions:

Professor, Department of Chemical Biology, College of Chemistry; Member of Chinese Academy of Sciences (CAS), 1991-; Advisory Editor of “Radiochimica Acta”, 1990-; Guest Professor of Institute of High Energy, CAS, 2002-; Vice-Chairman of International Committee of Asian-Pacific Conference on Radiochemistry, 2002-; Member of Consultant Commission of Chemistry Division, NSF, 2002-2006; Vice-Chair, Expert Commission of China’s High Level Waste Permanent Disposal, 2005-; Director, Institute of Nanochemistry & Nanobiology, Shanghai University, 2006-.

Past Academic Positions:

Titular Member, Commission on Nuclear and Radiochemistry, IUPAC, 1987-1995; Chairman, Commission on Nuclear and Radiochemistry, IUPAC, 1993-1995; Vice-Chairman of Chemistry Division, Chinese Academy of Sciences (CAS), 1992-2004.

Selected Publications：

1. Li H., Wang H., Liu Y. et al., Binding of nitrobenzene to hepatic DNA and hemoglobin at low doses in mice, Toxicol. Lett. 139, 25-32 (2003).
2. Cheng Y, Li HL, Liu YF et al., Inhibition of nicotine-DNA adduct formation in mice by six dietary constituents, Food Chem. Toxicol., 41, 1045-1050 (2003).
3. Li HL, Wang HF, Liu YF et al., Binding of nitrobenzene to hepatic DNA and hemoglobin at low doses in mice. Toxicol. Lett. 139-146, 25 (2003).
4. Wang HF, Liu YF, Zhao YL et al., Biodistribution of carbon single-wall nanotubes in mice. J. Nanosci. Nanotech. 4 (8), 1019-1024 (2004).
5. Xie QY, Sun HF, Liu YF et al., Adduction of acrylamide (AA) with biomacromolecules in mice at environmental dose levels studied by accelerator mass spectrometry, Toxicol. Lett. 163, 101-108 (2006).
6. Yuanfang Liu, Haifang Wang, Nanotechnology tackles tumours, Nature Nanotechnol. 2 (1), 20-21 (2007).