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李子臣 当前位置: 北京大学化学与分子工程学院课题组高分子化学 李子臣

李子臣

博士,教授,博士生导师
Tel:+86-10-62755543
Fax: +86-10-62751708
E-mail: zcli@pku.edu.cn

 

简历

1987.7 在山东大学化学系获理学学士学位
1990.8在中科院化学研究所获硕士学位
1990.9考入北京大学攻读博士学位,其中1993.8-1994.7在日本早稻田大学联合培养一年,1995.1获北京大学博士学位
1995.1-1996.12在北京大学化学学院从事博士后研究,其中1996.3-1996.5,1996.7-1996.12,作为日本学术振兴会特别研究员赴早稻田大学合作研究
1997.1起在北京大学化学学院工作,任讲师;1997.8晋升为副教授;2002.8晋升为教授。

研究方向

高分子合成化学
聚合反应新方法(多组分聚合,原子转移自由基聚加成)
序列、立构可控聚合物
刺激响应性高分子及其生物医学应用
自降解高分子材料

中国化学会,美国化学会,日本高分子学会 会员
中国化学会高分子学科委员会 委员、秘书长(2010-)
亚洲高分子学会联合会 理事(2008-)
IUPAC 高分子部门国家代表(2006-2010)
“Chinese J. Polym. Sci.” 常务副主编(2014-) “Polymer” (Elsevier, 2013-); “J. Mater. Chem. B” (RSC, 2014-); “Polymer International” (Wiley, 2014-); Editorial Board Member
《高分子学报》、《高等学校化学学报》、《高分子通报》和《功能高分子学报》编委。

教学工作

1. 讲授化学学院本科生必修课“高分子化学”
2. 讲授化学学院研究生选修课“功能高分子化学”

主要获奖

2003年获中国化学会青年化学奖
2004年入选教育部“新世纪优秀人才支持计划”
2005年获国家教学成果二等奖 (第5完成人)
2009年获“北京市优秀教师”荣誉称号
2010年获Feng Xinde Polymer Prize for “The best paper from China” published in the journal of “Polymer” during 2009
2012年获得国家杰出青年基金
2014年获国家教学成果二等奖 (第3完成人)


近5年发表的代表性学术论文

  1. Lv, A.; Li, Z.-L.; Du, F.-S.; Li, Z.-C. Synthesis, Functionalization, and Controlled Degradation of High Molecular Weight Polyester from Itaconic Acid via ADMET Polymerization, Macromolecules 2014, 47, 7707-7716.
  2. Li, Z.-L.; Lv, A.; Du, F.-S.; Li, Z.-C. Intrachain Cyclization via Postmodification of the Internal Alkenes of Periodic ADMET Copolymers: The Sequence Matters, Macromolecules 2014, 47, 5942-5951.
  3. Li, L.; Deng, X.-X.; Li, Z.-L.; Du, F.-S.; Li, Z.-C. Multifunctional Photodegradable Polymers for Reactive Micropatterns, Macromolecules 2014, 47, 4660-4667.
  4. Deng, X.-X.; Du, F.-S.; Li, Z.-C. Combination of Orthogonal ABB and ABC Multicomponent Reactions toward Efficient Divergent Synthesis of Dendrimers with Structural Diversity, ACS Macro Letters, 2014, 3, 667-670.
  5. Ji, R.; Cheng, J.; Yang, T.; Song, C. C.; Li, L.; Du, F.-S.; Li, Z.-C. Shell-Sheddable, pH-Sensitive Supramolecular Nanoparticles Based on Ortho Ester-Modified Cyclodextrin and Adamantyl PEG, Biomacromolecules 2014, 15, 3531-3569.
  6. C.-H. Wang, Z.-Y. Song, X.-X. Deng, L.-J. Zhang, F.-S. Du, Z.-C. Li, Combination of ATRA and ATRC for the Synthesis of Periodic Vinyl Copolymers, Macromol. Rapid Commun. 2014, 35, 474-478.
  7. X.-X. Deng, Y. Cui, F.-S. Du, Z.-C. Li, Functional highly branched polymers from multicomponent polymerization (MCP) based on the ABC type Passerini reaction, Polym. Chem. 2014, 5, 3316-3320.
  8. T. Yang, R. Ji, X. X. Deng, F. S. Du, Z. C. Li, Glucose-responsive hydrogels based on dynamic covalent chemistry and inclusion complexation, Soft Matter 2014, 10, 2671-2678.
  9. C.-C. Song, F.-S. Du, Z.-C. Li, Oxidation-responsive polymers for biomedical applications , J. Mater. Chem. B 2014, 2, 3413-3426.
  10. Zhang, L.-J.; Deng, X.-X.; Du, F.-S.; Li, Z.-C. Chemical Synthesis of Functional Poly(4-hydroxybutyrate) with Controlled Degradation via Intramolecular Cyclization, Macromolecules 2013, 46, 9554-9562.
  11. Song, C.-C.; Ji, R.; Du, F.-S.; Li, Z.-C. Oxidation-Responsive Poly(amino ester)s Containing Arylboronic Ester and Self-Immolative Motif: Synthesis and Degradation Study, Macromolecules 2013, 46, 8416-8425.
  12. Qiao, Z.-Y.; Ji, R.; Huang, X.-N.; Du, F.-S.; Zhang, R.; Liang, D.-H.; Li, Z.-C. Polymersomes from Dual Responsive Block Copolymers: Drug Encapsulation by Heating and Acid-Triggered Release, Biomacromolecules 2013, 14, 1555-1563.
  13. Song, C.-C.; Su, C.-C.; Cheng, J.; Du, F.-S.; Liang, D.-H.; Li, Z.-C. Toward Tertiary Amine-Modulated Acid-Triggered Hydrolysis of Copolymers Containing Pendent Ortho Ester Groups, Macromolecules 2013, 46, 1093-1100.
  14. Song, C.-C.; Ji, R.; Du, F.-S.; Liang, D.-H.; Li, Z.-C. Oxidation-Accelerated Hydrolysis of the Ortho Ester-Containing Acid-Labile Polymers, ACS Macro Letters 2013, 2,273-277.
  15. Li, L.; Lv, A.; Deng, X.-X.; Du, F.-S.; Li, Z.-C. Facile synthesis of photo-cleavable polymers via Passerini reaction Chem. Commun., 2013, 49, 8549-8551.
  16. Wang, Y. Z.; Deng, X. X.; Li, L.; Li, Z. L.; Du, F. S.; Li, Z. C. One-pot synthesis of polyamides with various functional side groups via Passerini reaction, Polym. Chem. 2013, 4, 444-448.
  17. Lv, A.; Deng, X.-X.; Li, L.; Li, Z.-L.; Wang, Y.-Z.; Du, F.-S.; Li, Z. Facile Synthesis of Multi-block Copolymers Containing Poly(ester-amide) Segments with Ordered Side Group Sequence, Polym. Chem. 2013, 4, 3659-3662.
  18. Li, Z.-L.; Lv, A.; Li, L.; Deng, X.-X.; Zhang, L.-J.; Du, F.-S.; Li, Z.-C. Periodic ethylene-vinyl alcohol copolymers via ADMET polymerization: Synthesis, characterization, and thermal property, Polymer 2013, 54, 3841-3849.
  19. Zhang, L.-J.; Dong, B.-T.; Du, F.-S.; Li, Z.-C. Degradable Thermoresponsive Polyesters by Atom Transfer Radical Polyaddition and Click Chemistry, Macromolecules 2012, 45, 8580-8587.
  20. Li, Z.-L.; Li, L.; Deng, X.-X.; Zhang, L.-J.; Dong, B.-T.; Du, F.-S.; Li, Z.-C. Periodic Vinyl Copolymers Containing γ-Butyrolactone via ADMET Polymerization of Designed Diene Monomers with Built-in Sequence, Macromolecules 2012, 45, 4590-4598.
  21. Lai, H.G.; Chen, G.T.; Wu, P.Y.; Li, Z.-C. Thermoresponsive behavior of an LCST-type polymer based on a pyrrolidone structure in aqueous solution, Soft Matter 2012, 8. 2662-2670.
  22. Dong, B.-T.; Li, Z.-L.; Zhang, L.-J.; Du, F.-S.; Li, Z.-C. Synthesis of linear functionalized polyesters by controlled atom transfer radical polyaddition reactions, Polym. Chem. 2012, 3, 2523-2530.
  23. Deng, X.-X.; Li, L.; Li, Z.-L.; Lv, A.; Du, F.-S.; Li, Z.-C. Sequence Regulated Poly(ester-amide)s Based on Passerini Reaction, ACS Macro Letters 2012,1,1300-303.
  24. Cheng, J.; Ji, R.; Gao, S.-J.; Du, F.-S.; Li, Z.-C. Facile Synthesis of Acid-Labile Polymers with Pendent Ortho Esters, Biomacromolecules 2012, 13, 173-179.
  25. Wang, Y.; Zhang, R.; Xu, N.; Du, F. S.; Wang, Y. L.; Tan, Y. X.; Ji, S. P.; Liang, D. H.; Li, Z. C. Reduction-Degradable Linear Cationic Polymers as Gene Carriers Prepared by Cu(I)-Catalyzed Azide-Alkyne Cycloaddition, Biomacromolecules 2011, 12, 66-74.
  26. Qiao, Z. Y.; Zhang, R.; Du, F. S.; Liang, D. H.; Li, Z. C. Multi-responsive nanogels containing motifs of ortho ester, oligo(ethylene glycol) and disulfide linkage as carriers of hydrophobic anti-cancer drugs, Journal of Controlled Release 2011, 152, 57-66.
  27. Chen, G. T.; Wang, C. H.; Zhang, J. G.; Wang, Y.; Zhang, R.; Du, F. S.; Yan, N.; Kou, Y. A.; Li, Z. C. Toward Functionalization of Thermoresponsive Poly(N-vinyl-2- pyrrolidone), Macromolecules 2010, 43, 9972.
  28. Dong, B. T.; Dong, Y. Q.; Du, F. S.; Li, Z. C. Controlling Polymer Topology by Atom Transfer Radical Self-Condensing Vinyl Polymerization of p-(2-Bromoiso- butyloylmethyl)styrene, Macromolecules 2010, 43, 8790.
  29. Qiao, Z. Y.; Du, F. S.; Zhang, R.; Liang, D. H.; Li, Z. C. Biocompatible Thermoresponsive Polymers with Pendent Oligo(ethylene glycol) Chains and Cyclic Ortho Ester Groups, Macromolecules 2010, 43, 6485.
  30. Zhang, C.; Gao, S. J.; Jiang, W.; Lin, S.; Du, F. S.; Li, Z. C.; Huang, W. L. Targeted minicircle DNA delivery using folate-poly(ethylene glycol)-polyethylenimine as non-viral carrier, Biomaterials 2010, 31, 6075.
  31. Wang, R.; Xu, N.; Du, F. S.; Li, Z. C. Facile control of the self-assembled structures of polylysines having pendent mannose groups via pH and surfactant, Chemical Communications 2010, 46, 3902.
  32. Deng, L.; Wang, C. H.; Li, Z. C.; Liang, D. H. Re-examination of the "Zipper Effect" in Hydrogen-Bonding Complexes, Macromolecules 2010, 43, 3004.
  33. Du, F. S.; Wang, Y.; Zhang, R.; Li, Z. C. Intelligent nucleic acid delivery systems based on stimuli-responsive polymers, Soft Matter 2010, 6, 835.
  34. Du, F. S.; Huang, X. N.; Chen, G. T.; Lin, S. S.; Liang, D. H.; Li, Z. C. Aqueous Solution Properties of the Acid-Labile Thermoresponsive Poly(meth)acrylamides with Pendent Cyclic Orthoester Groups, Macromolecules 2010, 43, 2474.
  35. Yan, N.; Zhang, J. G.; Yuan, Y.; Chen, G. T.; Dyson, P. J.; Li, Z. C.; Kou, Y. Thermoresponsive polymers based on poly-vinylpyrrolidone: applications in nanoparticle catalysis, Chemical Communications 2010, 46, 1631.
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